2B. S. aureus hemolysin B attacks the RBC cell membrane by hydrolyzing the sphingomyelin headgroup: OH HN. .R hemolysin B cuts this bond i) Draw a plausible mechanism of hydrolysis for this lipid headgroup. Let B- and BH be general base and general acid. e0-P-0 LOR2 OR, ii) Why is this damaging to the overall membrane architecture of the RBC?

Biochemistry
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ISBN:9781319114671
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Chapter1: Biochemistry: An Evolving Science
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2B. S. aureus hemolysin B attacks the RBC cell membrane by hydrolyzing the sphingomyelin headgroup:
N-
OH
HN.
hemolysin B
cuts this bond
i) Draw a plausible mechanism of hydrolysis for this lipid headgroup. Let B- and BH be general base and
general acid.
LOR2
OR,
ii) Why is this damaging to the overall membrane architecture of the RBC?
Transcribed Image Text:2B. S. aureus hemolysin B attacks the RBC cell membrane by hydrolyzing the sphingomyelin headgroup: N- OH HN. hemolysin B cuts this bond i) Draw a plausible mechanism of hydrolysis for this lipid headgroup. Let B- and BH be general base and general acid. LOR2 OR, ii) Why is this damaging to the overall membrane architecture of the RBC?
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