Reverse Transcription Black-viral genome IRNA (A) Green-tRNA from host R US PBS (-)ssDNA PPT U3 R (-) Strand Synthesis Red- minus strand DNA (B) Blue-plus strand DNA PPT First Strand Transfer RUS (C) U3R (-) Strand Synthesis PPT US R US (D) HIV ppt: PBS 5'-AAAAGAAAAGGGGGG-32 (-) & (+) Strand Synthesis (E) US R US (+) Strand Synthesis PPT PPT (F) U3 R US Second Strand Transfer U3 R US PBS - US PBS R US (+)ssDNA (G) US R US (H) LTR Strand displacement synthesis PPT PPT US R US LTR Basu et al., Virus Res. 2008, 134:19-38. Use the image above to answer the multiple choice question. If an infection with HIV is carried out with a virus that has a mutation that prevents reverse transcriptase from recognizing the polypurine tract (PPT), which of the following would be observed. No viral DNA would be observed Complete viral double strand DNA would be observed. Only a small piece of minus sense DNA would be observed. Nearly completed minus sense but no plus sense DNA would be observed. Nearly full length minus sense DNA but just a small pieces of plus sense DNA would be observed
Reverse Transcription Black-viral genome IRNA (A) Green-tRNA from host R US PBS (-)ssDNA PPT U3 R (-) Strand Synthesis Red- minus strand DNA (B) Blue-plus strand DNA PPT First Strand Transfer RUS (C) U3R (-) Strand Synthesis PPT US R US (D) HIV ppt: PBS 5'-AAAAGAAAAGGGGGG-32 (-) & (+) Strand Synthesis (E) US R US (+) Strand Synthesis PPT PPT (F) U3 R US Second Strand Transfer U3 R US PBS - US PBS R US (+)ssDNA (G) US R US (H) LTR Strand displacement synthesis PPT PPT US R US LTR Basu et al., Virus Res. 2008, 134:19-38. Use the image above to answer the multiple choice question. If an infection with HIV is carried out with a virus that has a mutation that prevents reverse transcriptase from recognizing the polypurine tract (PPT), which of the following would be observed. No viral DNA would be observed Complete viral double strand DNA would be observed. Only a small piece of minus sense DNA would be observed. Nearly completed minus sense but no plus sense DNA would be observed. Nearly full length minus sense DNA but just a small pieces of plus sense DNA would be observed
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Question

Transcribed Image Text:Reverse Transcription
Black-viral genome
IRNA
(A)
Green-tRNA from host
R US PBS
(-)ssDNA
PPT
U3 R
(-) Strand Synthesis
Red- minus strand DNA
(B)
Blue-plus strand DNA
PPT
First Strand Transfer
RUS
(C)
U3R
(-) Strand Synthesis
PPT
US R US
(D)
HIV ppt:
PBS
5'-AAAAGAAAAGGGGGG-32
(-) & (+) Strand Synthesis
(E)
US R US
(+) Strand Synthesis
PPT
PPT
(F)
U3 R US
Second Strand Transfer
U3 R US
PBS
-
US PBS
R US
(+)ssDNA
(G)
US R US
(H)
LTR
Strand displacement synthesis
PPT
PPT
US R US
LTR
Basu et al., Virus Res. 2008, 134:19-38.
Use the image above to answer the multiple choice
question. If an infection with HIV is carried out with a
virus that has a mutation that prevents reverse
transcriptase from recognizing the polypurine tract (PPT),
which of the following would be observed.
No viral DNA would be observed
Complete viral double strand DNA would be observed.
Only a small piece of minus sense DNA would be observed.
Nearly completed minus sense but no plus sense DNA would
be observed.
Nearly full length minus sense DNA but just a small pieces of
plus sense DNA would be observed
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