Y 3' W

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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**DNA Replication: Identifying Leading and Lagging Strands**

In this educational diagram, we are examining a DNA replication fork. Two parental DNA strands are illustrated, which serve as templates for the synthesis of new strands. The diagram is labeled with:

- **W, X, Y, Z:** These are placeholders for the new strands being synthesized.
- **3' and 5':** These numbers indicate the directionality of the DNA strands.

**Detailed Explanation of Components:**

- **W and X:** Represent the new strands synthesized along the template. One of these will be the leading strand and the other the lagging strand.
  
- **Y and Z:** Also represent new strands. Similarly, one will be leading and the other lagging.

**Strand Roles in Replication:**

- **Leading Strand (A):** This strand is synthesized continuously in the 5' to 3' direction, following the replication fork as it opens.
- **Lagging Strand (B):** This strand is synthesized discontinuously in short segments called Okazaki fragments, and also in the 5' to 3' direction, but moving away from the replication fork.

**Task:**

- Match each of the strands labeled W, X, Y, and Z to their role in replication, as either leading or lagging.

Understanding which strands function as leading or lagging is essential for grasping how DNA replication ensures accurate genetic information transfer.
Transcribed Image Text:**DNA Replication: Identifying Leading and Lagging Strands** In this educational diagram, we are examining a DNA replication fork. Two parental DNA strands are illustrated, which serve as templates for the synthesis of new strands. The diagram is labeled with: - **W, X, Y, Z:** These are placeholders for the new strands being synthesized. - **3' and 5':** These numbers indicate the directionality of the DNA strands. **Detailed Explanation of Components:** - **W and X:** Represent the new strands synthesized along the template. One of these will be the leading strand and the other the lagging strand. - **Y and Z:** Also represent new strands. Similarly, one will be leading and the other lagging. **Strand Roles in Replication:** - **Leading Strand (A):** This strand is synthesized continuously in the 5' to 3' direction, following the replication fork as it opens. - **Lagging Strand (B):** This strand is synthesized discontinuously in short segments called Okazaki fragments, and also in the 5' to 3' direction, but moving away from the replication fork. **Task:** - Match each of the strands labeled W, X, Y, and Z to their role in replication, as either leading or lagging. Understanding which strands function as leading or lagging is essential for grasping how DNA replication ensures accurate genetic information transfer.
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