Please describe the regulatory role of enhancers that binds to responsible regulators to activate the target gene at a given time and place through comparing different organisms according to the presence of regulatory sequences.

Q: Explain the several reasons on additional levels of complexity are both possible and necessary for…

A: Gene expression is a complex process that is mediated by several processes. There are around 20,000…

Q: This image shows the alignment of the promoter from the same gene (gene H) across multiple mammalian…

A: Introduction  The central promoter region of genes in archaea and eukaryotes contain a DNA sequence…

Q: Please explain the role of the SRP, SRP receptor and the protein translocator in the synthesis of a…

A: After the proteins has been translated, it needs to be send to different areas in the cells to carry…

Q: What would be the likely phenotypic effect of a mutation in HOTAIR and prevented it from binding to…

A: HOTAIR (HOX antisense intergenic RNA) is a long non-coding RNAs with 6 exons and 2158 nucleotides…

Q: what do you predict is a likely outcome in mice with the bat-mouse construct? Select one 1.) change…

A: Regulatory "switches" are found upstream from a gene. Regulatory molecules bind to the switches and…

Q: Debes et al recently described how aging in humans, mice, nematodes, and other eukaryotes is…

A: Mediator Proteins:Prediction: Overexpression of Mediator proteins would likely reduce…

Q: Understanding why these receptors are present when they are not supposed to be is important in…

A: When there is methylation at the cytosines present in promoter the genes are silenced as they blocks…

Q: To identify transcriptional regulatory elements, reporters containing 100 base pairs of Promoter…

A: Transcriptional regulatory elements are the genetic segments that act as the binding sites for…

Q: Explain why the glucocorticoid receptor binds next to the core promoter of some genes, but not next…

A: Gene expression is a process in which the information present in the particular sequences is…

Q: Propose a strategy to prevent HIF-alpha signaling in the TME. What do you think would happen in a…

A: The oxygen-sensitive transcriptional activator HIF-1 (hypoxia-inducible factor-1) is an important…

Q: You have isolated a protein that binds to DNA in the region upstream of the promoter sequence of a…

A: The promoter is the site of RNA polymerase binding that is very important step in the initiation…

Q: Describe and explain the 3-D structural change to the protein (uniprotkb-p39086/gene regulator 5)…

A: Answer-- 3-D structure of proteins is the level of protein structure at which an entire polypeptide…

Q: Please describe the regulatory role of enhancers that binds to responsible regulators to activate…

A: An enhancer is a regulatory DNA molecule comprising 200 base pairs. Enhancers are also known as…

Q: a. How many enhancers were you able to identify with these set of experiments? Explain. b. If you…

A: Enhancers are the term used for the regions of DNA (deoxyribonucleic acid) that elevate the…

Q: Comparison of different tissues shows that the ITY gene produces a 900 nt mature mRNA and a 190…

A: Alternative splicing is the mechanism that produces multiple mature mRNAs from a single primary…

Q: Briefly describe how the transcript beginning at the lambda PRe promoter can inhibit expression of…

A: The Cro protein is an effective and specific repressor of the RNA synthesis from the N and the cro…

Q: Can expression or the timing of expression of therapeuticgenes be controlled in a patient so that…

A: In genetics, gene therapy is defined as the introduction of the genetic material  in the DNA in…

Q: During certain stages of development, the requirement forcertain gene products may require gene…

A: A gene is a stretch of nucleotides present in the DNA. It codes for the synthesis of an RNA or…

Q: ith examples explain the importance of Non-coding ribonucleic acid interference in regards to gene…

A: A DNA sequence's genes are translated into amino acid sequences during the process of gene…

Q: Outline the two ways that piRNAs and PIWI proteins inhibit transposable elements.

A: PIWI (P- element Induced Wimpy testis) are RNA (Ribonucleic acid) binding regulatory proteins. The…

Q: Discuss the structure and function of regulatory elements. Where are they located relative to the…

A: A eukaryotic organism is made up of several genes. It is essential to ensure that not all genes are…

Q: Explain how HOTAIR plays a role in the transcriptional regulationof particular genes.

A: A gene is a sequence of nucleotides in genome that codes for a functioning molecule. There is…

Q: How do activators bind enhancers in the first place if the enhancer DNA is covered with nucleosomes?

A: In the nucleus of each cell in higher organisms, the DNA molecule is packaged into thread-like…

Q: What molecular genetic method(s) or approaches would you use to test whether a transcription factor…

A: Transcription refers to the molecular process by which a cell synthesizes RNA from its genetic…

Q: You have identified an enhancer that drives Pax6 expression in the developing lens and cornea of the…

A: To explain in more detail, we need to break down the process step by step and analyze the northern…

Q: RNAP can access the lacZ promoter irrespective of whether CAP-CAMP is binding the CAP o True False

A: Lac operon is a set of structural genes regulated by a common promoter. It is found in bacteria.

Q: In any experiment, controls are essential in order to determine the specific effect of changing some…

A: Controls are used in the experiment to analyze the obtained results and reach a conclusion on…

Q: Upon identification of the DNA regulatory sequence responsible for translating a given gene, you…

A: The regulatory proteins binding along with enhancer sequence will result in a shift that occurs in…

Q: The extent to which a given gene is transcribe depends on 1. the particular combination of…

A: Introduction: The biological process involving the copying of the information present in the strand…

Q: In Figure 13-5, two different methods are illustrated forvisualizing gene expression in developing…

A: Gene expression is the very important phenomenon which is almost occurs in every living organisms.…

Q: Describe the methods used to identify the location of transcription control elements in promoter…

A: The sequence of nucleotides in a gene that controls gene transcription is known as a transcriptional…

Q: You are studying how the expression of Gene F is regulated. Initially, you identified three…

A: Step 1:To determine if any of the potential regulatory elements bind a transcriptional activator, we…

Q: One of the main lessons of this chapter is that several bacterial genes are often transcribed from a…

A: As given: Several bacterial genes are often transcribed from a single promoter into a large…

Q: Organisms must rapidly acclimate to changes in their environment. For instance, temperature changes…

A: Octopus bimaculoides often called "bimac" is an octopus species that belongs to class cephalopoda.…

Q: al4 is a transcription factor that activates transcription of galactose metabolism genes in yeast.…

A: Glycolysis is a primary source of energy in yeast, and glucose is by far the most favored carbon…

Q: An abundance of misfolded proteins in the ER can result in the activation of the unfolded-protein…

A: Endoplasmic Reticulum can be referred to as one of the organelles of cell that can be observed in…

Q: State whether each of the following would be likely to (generally) increase or decrease the…

A: Gene expression regulation involves the modification of both the DNA and the packaging proteins…

Q: which laboratory method can be used to quantify levels of mRNAs expressed in samples of two…

A: Biological approaches are a well-developed field in process technology for treating a wide range of…

Q: Can methylation state of the promoter influence the level of gene expression? Briefly describe how…

A: In eukaryotes, DNA methylation occurs by an enzyme known as DNA methyltransferase. Where the…

Q: Compare the auto induction media (AIM) with regular induced protein expression. Which is better when…

A: Most of the eukaryotic proteins are still produced via genetic engineering it into host prokaryotic…

Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.