PedigreesQuestion 1In the following human pedigrees, the filled symbols represent the affected individuals. You may assume that thedisease allele is rare and therefore individuals marrying into the family are unlikely to have defective allele.a)i) What is the most likely mode of inheritance for this pedigree?Autosomal dominantii) State the genotypes of individuals # 1-5 in the following table using the letter "A". Use the uppercaseletter to represent the dominant allele and lowercase letter to represent the recessive allele.IndividualGenotype#1#3#4#5iii) If individuals # 2 and 3 have another son what are the chances that this son will be affected?50% (Aa x aa)b)6.78i) What is the most likely mode of inheritance for this pedigree?ii) State the genotypes of individuals # 6-8 in the following table using the letter "B". Use the uppercaseletter to represent the dominant allele and lowercase letter to represent the recessive allele.IndividualGenotype#6#7#8iii) If Individuals #6 and #7 have another daughter what are the chances that she will be affected.Question 2You are analyzing the following human pedigree.Assume that the individual marked with an asterisk (*) does not carry any allele associated with the affectedphenotype and that no other mutation spontaneously occurs. Also assume complete penetrance. Use "R or XR"for the allele associated with the dominant phenotype, "r or X" for the allele associated with the recessivephenotype.2affected femaleUnaffected femaleaffected maleUnaffected maleBa) What is the most likely mode of inheritance of this disease? Choose from: autosomal dominant, autosomalrecessive, X-linked dominant, X-linked recessive.b) List all possible genotypes of the following individuals in the pedigree.IndividualsGenotypes#1#3c) What is the probability of Individual A being affected?d) What is the probability of Individual B being affected?

Name: PedigreesQuestion 1In the following human pedigrees, the filled symbo
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Description: PedigreesQuestion 1In the following human pedigrees, the filled symbols represent the affected individuals. You may assume that thedisease allele is rare and therefore individuals marrying into the family are unlikely to have defective allele.a)i) W