Answered: Cancer Precancerous O growth 4 8295…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question

Pancreatic cancer is clearly inherited as an autosomal dominant trait in the family illustrated in Figure 23.1. Yet most cases of pancreatic cancer are sporadic, appearing as isolated cases in families with no obvious inheritance. How can a trait be strongly inherited in one family and not inherited in another?

Cancer
Precancerous O
growth
4
8295
23.1 Pancreatic cancer is inherited as an autosomal dominant trait in a
family that possesses a mutated palladin gene.

Expert Solution

Step 1

Cancer is an uncontrolled division of cell that has a defunct apoptosis mechanism. Usually, when cells come in close proximity to each other, they tend to get destroyed. This is a property of cell called as contact inhibition. But cancerous cells lack this property and hence they accumulate together and continue to divide in an uncontrolled manner thereby leading to tumors.

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