he propensity to develop retinal cancer can run in pedigrees of certain families. You have learned about the role of the retinoblastoma (Rb) protein in the cell cycle. A heterozygous individual (genotype = Rbm / Rb+) that inherits a mutant allele of the Rb gene (Rbm) as well as a normal allele of the Rb gene (Rb+) is at significant risk for developing cancer of the retina. The best explanation for this is that… A. the Rb(m) allele is dominant to the Rb(+) allele. B.  a mutation in the Rb(+) allele can result in a Rb(m) / Rb(m) genotype in certain cells. C.  the retina is frequently exposed to UV rays D.  the Rb(m) allele directly converts the Rb(+) allele to another Rb(m) allele. E.  the cells of the retina carry more than two copies of the Rb gene

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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The propensity to develop retinal cancer can run in pedigrees of certain families. You have learned about the role of the retinoblastoma (Rb) protein in the cell cycle. A heterozygous individual (genotype = Rbm / Rb+) that inherits a mutant allele of the Rb gene (Rbm) as well as a normal allele of the Rb gene (Rb+) is at significant risk for developing cancer of the retina. The best explanation for this is that…

A. the Rb(m) allele is dominant to the Rb(+) allele.

B.  a mutation in the Rb(+) allele can result in a Rb(m) / Rb(m) genotype in certain cells.

C.  the retina is frequently exposed to UV rays

D.  the Rb(m) allele directly converts the Rb(+) allele to another Rb(m) allele.

E.  the cells of the retina carry more than two copies of the Rb gene

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