1 at birth 1 2 This pedigree illustrates the occurrence of neurofibromatosis in a small human family (filled symbols represent people with neurofibromatosis). Match individual II-2 in this pedigree to their most likely genotype at birth, in adult tumor cells, and adult somatic cells that are not part of any tumor. Genotypes may be chosen more than once, and not all genotypes need to be chosen. NF1+ denotes a wild type allele (i.e. NF1+/NF1+ is homozygous wild type) NF1- denotes a loss of function mutant allele NF1++ denotes a gain of function mutant allele adult tumor cells 2 3 adult somatic cells not in a tumor ✓ [Choose ] NF1+/NF1+ NF1+/NF1- NF1+/NF1++ NF1++/NF1++ NF1-/NF1- [Choose ]

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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||
(1
at birth
2
1 2 3
This pedigree illustrates the occurrence of neurofibromatosis in a small human
family (filled symbols represent people with neurofibromatosis). Match individual
II-2 in this pedigree to their most likely genotype at birth, in adult tumor cells,
and adult somatic cells that are not part of any tumor. Genotypes may be chosen
more than once, and not all genotypes need to be chosen.
NF1+ denotes a wild type allele (i.e. NF1+/NF1+ is homozygous wild type)
NF1- denotes a loss of function mutant allele
NF1++ denotes a gain of function mutant allele
adult tumor cells
adult somatic cells not in a tumor
✓ [Choose ]
NF1+/NF1+
NF1+/NF1-
NF1+/NF1++
NF1++/NF1++
NF1-/NF1-
[Choose ]
Transcribed Image Text:|| (1 at birth 2 1 2 3 This pedigree illustrates the occurrence of neurofibromatosis in a small human family (filled symbols represent people with neurofibromatosis). Match individual II-2 in this pedigree to their most likely genotype at birth, in adult tumor cells, and adult somatic cells that are not part of any tumor. Genotypes may be chosen more than once, and not all genotypes need to be chosen. NF1+ denotes a wild type allele (i.e. NF1+/NF1+ is homozygous wild type) NF1- denotes a loss of function mutant allele NF1++ denotes a gain of function mutant allele adult tumor cells adult somatic cells not in a tumor ✓ [Choose ] NF1+/NF1+ NF1+/NF1- NF1+/NF1++ NF1++/NF1++ NF1-/NF1- [Choose ]
||
1 2
1 2 3
This pedigree illustrates the occurrence of neurofibromatosis in a small human
family (filled symbols represent people with neurofibromatosis). Match individual
II-2 in this pedigree to their most likely genotype at birth, in adult tumor cells,
and adult somatic cells that are not part of any tumor. Genotypes may be chosen
more than once, and not all genotypes need to be chosen.
NF1+ denotes a wild type allele (i.e. NF1+/NF1+ is homozygous wild type)
NF1- denotes a loss of function mutant allele
at birth
NF1++ denotes a gain of function mutant allele
adult tumor cells
adult somatic cells not in a tumor
[Choose ]
✓ [Choose ]
NF1+/NF1+
NF1+/NF1-
NF1+/NF1++
NF1++/NF1++
NF1-/NF1-
Transcribed Image Text:|| 1 2 1 2 3 This pedigree illustrates the occurrence of neurofibromatosis in a small human family (filled symbols represent people with neurofibromatosis). Match individual II-2 in this pedigree to their most likely genotype at birth, in adult tumor cells, and adult somatic cells that are not part of any tumor. Genotypes may be chosen more than once, and not all genotypes need to be chosen. NF1+ denotes a wild type allele (i.e. NF1+/NF1+ is homozygous wild type) NF1- denotes a loss of function mutant allele at birth NF1++ denotes a gain of function mutant allele adult tumor cells adult somatic cells not in a tumor [Choose ] ✓ [Choose ] NF1+/NF1+ NF1+/NF1- NF1+/NF1++ NF1++/NF1++ NF1-/NF1-
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