Osmotic experiment is done using equivalent dilutions of 2% urea. Note the erythrocyte membrane permeability constants (P) for urea, sodium (Na+) and chloride ions (Cl-) are 152, 0.25 and 0.1 x 10-4 cm.s-1, respectively. Select all of the following which apply. The permeability constants indicate that red blood cell membranes are much more permeable to urea, thus urea will enter the cells (a permeating solute) and exerts an osmotic effect with water leaving the cells. 1% NaCl is equivalent to 2% urea, because NaCl dissociates into Na+ and Cl-, thus resulting in a solution of the same osmolarity as the 2% urea, which does not dissociate.  The permeability constants indicate that red blood cell membranes are much more permeable to urea, thus urea will enter the cells (a permeating solute) and does not exert an osmotic effect. The permeability constants indicate that red blood cell membranes are much less permeable to urea, thus urea will not enter the cells (a permeating solute) and does not exert an osmotic effect. 1% NaCl is equivalent to 1% urea in terms of osmolarity, so 2% urea has twice the effect on the cells as 1% NaCl.  The permeability constants indicate that red blood cell membranes are much less permeable to urea, thus urea will enter the cells (a permeating solute) and does not exert an osmotic effect.

Biochemistry
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Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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Osmotic experiment is done using equivalent dilutions of 2% urea. Note the erythrocyte membrane permeability constants (P) for urea, sodium (Na+) and chloride ions (Cl-) are 152, 0.25 and 0.1 x 10-4 cm.s-1, respectively.

Select all of the following which apply.

The permeability constants indicate that red blood cell membranes are much more permeable to urea, thus urea will enter the cells (a permeating solute) and exerts an osmotic effect with water leaving the cells.

1% NaCl is equivalent to 2% urea, because NaCl dissociates into Na+ and Cl-, thus resulting in a solution of the same osmolarity as the 2% urea, which does not dissociate. 

The permeability constants indicate that red blood cell membranes are much more permeable to urea, thus urea will enter the cells (a permeating solute) and does not exert an osmotic effect.

The permeability constants indicate that red blood cell membranes are much less permeable to urea, thus urea will not enter the cells (a permeating solute) and does not exert an osmotic effect.

1% NaCl is equivalent to 1% urea in terms of osmolarity, so 2% urea has twice the effect on the cells as 1% NaCl. 

The permeability constants indicate that red blood cell membranes are much less permeable to urea, thus urea will enter the cells (a permeating solute) and does not exert an osmotic effect.

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