Answered: The membrane separating compartments A…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

The membrane separating compartments A and B of the following chamber is permeable to Cl- ions
(gCl = 5) but impermeable to water and K+. The initial concentrations of KCl in compartments A and
B, before diffusion has occurred, are presented below. Use this information to answer questions 9-12.
Note: Whenever necessary, consider compartment A as the ICF and compartment B as the ECF.

KCl = 10 mM

A

KCl = 150 mM

B

9. After equilibrium, the potential of compartment A will be _____mV (include polarity)
compared to a reference of 0 mV. Consider compartment B as the outside.

A) -70 mV
B) 70 mV
C) -90 mV
D) 90 mV

10. At equilibrium, the flux of Cl- from compartment A to compartment B will be ______ the flux
of Cl- from compartment B to compartment A.

A) equal to
B) less than
C) more than

11. Increasing the concentration of [Cl-] in compartment B from 150 mM to 200 mM will
______________.

A) make ECl more positive
B) make EK more negative
C) make ECl more negative
D) not change the value of ECl

4
12. If the conductance for Cl- (gCl) is increased from 5 to 10, the equilibrium potential for Cl- will:

A) become larger.
B) become smaller.
C) not change

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