The immediate effect of ADH on the renal tubules of frogs and mice is the same, yet when ADH is secreted, frogs produce urine that is approximately isosmotic to their blood plasma, whereas mice produce urine far more concentrated than their blood plasma. Explain this difference in terms of the factors affecting osmosis in the kidneys of frogs and mice.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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The immediate effect of ADH on the renal tubules of frogs and
mice is the same, yet when ADH is secreted, frogs produce urine
that is approximately isosmotic to their blood plasma, whereas
mice produce urine far more concentrated than their blood
plasma. Explain this difference in terms of the factors affecting
osmosis in the kidneys of frogs and mice.

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