Ion transporters are “linked” together—not physi-cally, but as a consequence of their actions. For example,cells can raise their intracellular pH, when it becomes tooacidic, by exchanging external Na+ for internal H+, usinga Na+–H+ antiporter. The change in internal Na+ is thenredressed using the Na+-K+ pump.A. Can these two transporters, operating together,normalize both the H+ and the Na+ concentrations insidethe cell?B. Does the linked action of these two pumps causeimbalances in either the K+ concentration or the mem-brane potential? Why or why not?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Ion transporters are “linked” together—not physi-
cally, but as a consequence of their actions. For example,
cells can raise their intracellular pH, when it becomes too
acidic, by exchanging external Na+ for internal H+, using
a Na+–H+ antiporter. The change in internal Na+ is then
redressed using the Na+-K+ pump.
A. Can these two transporters, operating together,
normalize both the H+ and the Na+ concentrations inside
the cell?
B. Does the linked action of these two pumps cause
imbalances in either the K+ concentration or the mem-
brane potential? Why or why not?

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