Here is a chloride cell in the gill epithelium of a fish. For reference, NKA = Na+/K+ ATPaseNKCC = Na+/K+/Cl- cotransporter. (image 1)The same proteins have been identified in shark rectal gland, marine birds and reptiles (salt glands in nostrils), marine fishes (chloride cells in their gills) and mammals that transport salt in their kidneys. (image 2)When biologists were testing the mechanism of salt excretion in sharks, they used a chemical called ouabain to inhibit the Na+/K+ ATPase to see if there was an effect. Which result would you expect to see with ouabain treatment? A.A decrease in Cl- in the epithelial cells. B.An increase in ADP in the epithelial cells. C.An increase in K+ in the epithelial cells. D.A decrease in Na+ in the epithelial cells. NaMRC2к-mV+mVNKANKCC3Na NaK 2CICFTR}-욕 PROCESS: MODEL OF SALT EXCRETION IN SHARK RECTAL GLANDcrNatLumen of rectal gland (empties into environment)ChloridechannelApical membraneEpithelial cell2K*20rNatATPADRBasolateralmembraneInterstitial fluid,near bloodvesselsNat/K*-Na*/CIK*PotasslumATPasecotransporterchannel3Na*1. Na'к*-АТРаsеpumps Na out of cellк*3. cr diffuses intolumen along itselectrochemical gradient.K* diffuses intointerstitial fluid.2. Na"/cr/Kcotransporter.4. Na' diffusesinte lumen.and K* Into celI.

Marine animals are living in an environment in which the salt concentration is very high. They are…

Answered: Na MRC 2к -mV+mV NKA NKCC 3Na Na K 2CI…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Here is a chloride cell in the gill epithelium of a fish. For reference, NKA = Na+/K+ ATPase
NKCC = Na+/K+/Cl- cotransporter. (image 1)

The same proteins have been identified in shark rectal gland, marine birds and reptiles (salt glands in nostrils), marine fishes (chloride cells in their gills) and mammals that transport salt in their kidneys. (image 2)

When biologists were testing the mechanism of salt excretion in sharks, they used a chemical called ouabain to inhibit the Na+/K+ ATPase to see if there was an effect. Which result would you expect to see with ouabain treatment?

	A.	A decrease in Cl- in the epithelial cells.
	B.	An increase in ADP in the epithelial cells.
	C.	An increase in K+ in the epithelial cells.
	D.	A decrease in Na+ in the epithelial cells.

Na
MRC
2к
-mV+mV
NKA
NKCC
3Na Na
K 2CI
CFTR}-욕

PROCESS: MODEL OF SALT EXCRETION IN SHARK RECTAL GLAND
cr
Nat
Lumen of rectal gland (empties into environment)
Chloride
channel
Apical membrane
Epithelial cell
2K*
20r
Nat
ATP
ADR
Basolateral
membrane
Interstitial fluid,
near blood
vessels
Nat/K*-
Na*/CIK*
Potasslum
ATPase
cotransporter
channel
3Na*
1. Na'к*-АТРаsе
pumps Na out of cell
к*
3. cr diffuses into
lumen along its
electrochemical gradient.
K* diffuses into
interstitial fluid.
2. Na"/cr/K
cotransporter.
4. Na' diffuses
inte lumen.
and K* Into celI.

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