Glucose enters erythrocytes via a GLUT-1uniporter. As the levels of glucose in thebloodstream decrease between meals,what happens to the glucose in the cells?O Glucose remains in the cell because theGLUT-1 uniporters are gated and the gatesclose at low glucose concentrationsGlucose leaves the cell through the GLUT-1uniporter, traveling down the newconcentration gradient.Glucose remains in the cell becauseuniporters can only transport in onedirection.Glucose remains in the cell because it hasbeen phosphorylated to Glucose-6-phosphate and no longer has affinity for theGLUT-1 uniporter

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Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Glucose enters erythrocytes via a GLUT-1
uniporter. As the levels of glucose in the
bloodstream decrease between meals,
what happens to the glucose in the cells?
O Glucose remains in the cell because the
GLUT-1 uniporters are gated and the gates
close at low glucose concentrations
Glucose leaves the cell through the GLUT-1
uniporter, traveling down the new
concentration gradient.
Glucose remains in the cell because
uniporters can only transport in one
direction.
Glucose remains in the cell because it has
been phosphorylated to Glucose-6-
phosphate and no longer has affinity for the
GLUT-1 uniporter

Expert Solution

Step 1: Phosphorylation

Upon entering erythrocytes (red blood cells) through the GLUT-1 uniporter, glucose undergoes immediate phosphorylation to create Glucose-6-phosphate, a process facilitated by the enzyme hexokinase. This phosphorylation step is irreversible in glucose metabolism.

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