A 55 year old woman was diagnosed as hypertensive by the GP but was failing to respond to medication for high blood pressure. They were also complaining of muscle weakness. Further blood tests revealed the following biochemical profile seen in the table below. Variable Urea (mm) Creatinine (mm) Na+ (mm) K+ (mm) Aldosterone (PM) Renin activity (RA) (nM/hr) Aldosterone/RA ratio Cortisol (nM) pH Result 6.6 79 165 2.4 762 0.29 2627 435 7.48 Reference Range 2.5-7.0 60 - 120 134-147 3.5-5.0 90-700 0.5-3.5 <680 138 - 690 7.35-7.45 a) What is the most likely diagnosis and also the underlying cause of the disorder? Explain your rationale for the cause of the disorder based on particular test results indicated in the table. (140 words)
A 55 year old woman was diagnosed as hypertensive by the GP but was failing to respond to medication for high blood pressure. They were also complaining of muscle weakness. Further blood tests revealed the following biochemical profile seen in the table below. Variable Urea (mm) Creatinine (mm) Na+ (mm) K+ (mm) Aldosterone (PM) Renin activity (RA) (nM/hr) Aldosterone/RA ratio Cortisol (nM) pH Result 6.6 79 165 2.4 762 0.29 2627 435 7.48 Reference Range 2.5-7.0 60 - 120 134-147 3.5-5.0 90-700 0.5-3.5 <680 138 - 690 7.35-7.45 a) What is the most likely diagnosis and also the underlying cause of the disorder? Explain your rationale for the cause of the disorder based on particular test results indicated in the table. (140 words)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Answer the question in 140 words
Transcribed Image Text:A 55 year old woman was diagnosed as hypertensive by the GP but was failing to respond to medication
for high blood pressure. They were also complaining of muscle weakness. Further blood tests revealed the
following biochemical profile seen in the table below.
Variable
Urea (mm)
Creatinine (mm)
Na+ (mm)
K+ (mm)
Aldosterone (PM)
Renin activity (RA)
(nM/hr)
Aldosterone/RA ratio
Cortisol (nM)
pH
Result
6.6
79
165
2.4
762
0.29
2627
435
7.48
Reference Range
2.5-7.0
60 - 120
134-147
3.5-5.0
90 - 700
0.5-3.5
<680
138 - 690
7.35-7.45
a) What is the most likely diagnosis and also the underlying cause of the disorder? Explain your
rationale for the cause of the disorder based on particular test results indicated in the table. (140
words)
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