9:58 ← LTE 43% PHGY 215 Applied Physi... Questions: 1. Using Table 3, which contains the normal intracellular ion concentrations for most cells in the body, calculate the equilibrium potential for each of the four ions for normal intracellular and normal extracellular ion concentrations. Make sure to show your calculations. Repeat these same calculations, only this time utilize the hyperkalemia values from Table 1. Table 3. Intracellular ion concentrations. lon Intracellular concentration (mM) 150 K+ Na* 15 CI Ca2+ 4 .0001 2. Using Table 4, which contains the relative ion permeabilities for neurons and cardiac myocytes at rest, calculate the resting membrane potentials for both neurons and cardiac myocytes. Make sure to include calculations for both hyperkalemia and normal plasma ion concentrations. Table 4. Relative ion permeabilities for neurons and cardiac myocytes. lon K+ Na+ Neuron relative permeability 1 .04 CI- .45 Cardiac myocyte relative permeability 1 0 0 3. Using Table 2, which shows the patient's plasma K* concentrations over a 24-hour period, graph the changes of K* over time. Make sure to include an appropriate figure caption to explain what you have observed and follow scientific best practices for creating your graph. (You may consult graphs in published physiology articles for inspiration!) 4. Based on the data provided to you within this case and your calculations, postulate as to why JH experienced more cardiac vs neuronal symptoms. Please answer this question in the context of your knowledge of Modules 1 and 2. You do not need to provide detailed information on cardiac physiology. 5. The image below depicts a histological slice of human cerebral cortex tissue III

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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9:58
←
LTE 43%
PHGY 215 Applied Physi...
Questions:
1. Using Table 3, which contains the normal intracellular ion concentrations for most cells in the body,
calculate the equilibrium potential for each of the four ions for normal intracellular and normal
extracellular ion concentrations. Make sure to show your calculations. Repeat these same calculations,
only this time utilize the hyperkalemia values from Table 1.
Table 3. Intracellular ion concentrations.
lon
Intracellular
concentration (mM)
150
K+
Na*
15
CI
Ca2+
4
.0001
2. Using Table 4, which contains the relative ion permeabilities for neurons and cardiac myocytes at rest,
calculate the resting membrane potentials for both neurons and cardiac myocytes. Make sure to include
calculations for both hyperkalemia and normal plasma ion concentrations.
Table 4. Relative ion permeabilities for neurons and cardiac myocytes.
lon
K+
Na+
Neuron
relative permeability
1
.04
CI-
.45
Cardiac myocyte
relative permeability
1
0
0
3. Using Table 2, which shows the patient's plasma K* concentrations over a 24-hour period, graph the
changes of K* over time. Make sure to include an appropriate figure caption to explain what you have
observed and follow scientific best practices for creating your graph. (You may consult graphs in published
physiology articles for inspiration!)
4. Based on the data provided to you within this case and your calculations, postulate as to why JH
experienced more cardiac vs neuronal symptoms. Please answer this question in the context of your
knowledge of Modules 1 and 2. You do not need to provide detailed information on cardiac physiology.
5. The image below depicts a histological slice of human cerebral cortex tissue
III
Transcribed Image Text:9:58 ← LTE 43% PHGY 215 Applied Physi... Questions: 1. Using Table 3, which contains the normal intracellular ion concentrations for most cells in the body, calculate the equilibrium potential for each of the four ions for normal intracellular and normal extracellular ion concentrations. Make sure to show your calculations. Repeat these same calculations, only this time utilize the hyperkalemia values from Table 1. Table 3. Intracellular ion concentrations. lon Intracellular concentration (mM) 150 K+ Na* 15 CI Ca2+ 4 .0001 2. Using Table 4, which contains the relative ion permeabilities for neurons and cardiac myocytes at rest, calculate the resting membrane potentials for both neurons and cardiac myocytes. Make sure to include calculations for both hyperkalemia and normal plasma ion concentrations. Table 4. Relative ion permeabilities for neurons and cardiac myocytes. lon K+ Na+ Neuron relative permeability 1 .04 CI- .45 Cardiac myocyte relative permeability 1 0 0 3. Using Table 2, which shows the patient's plasma K* concentrations over a 24-hour period, graph the changes of K* over time. Make sure to include an appropriate figure caption to explain what you have observed and follow scientific best practices for creating your graph. (You may consult graphs in published physiology articles for inspiration!) 4. Based on the data provided to you within this case and your calculations, postulate as to why JH experienced more cardiac vs neuronal symptoms. Please answer this question in the context of your knowledge of Modules 1 and 2. You do not need to provide detailed information on cardiac physiology. 5. The image below depicts a histological slice of human cerebral cortex tissue III
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