Mutation and protein analysis problems Name: Madison Lenhardt. 1. Geneticists interested in human hemoglobins have found a very large number of mutant forms. Some of these mutant proteins are of normal size, with amino acid substitutions, while others are short, due to deletions or nonsense mutations. The first extra-long example was named Hb Constant Spring, in which acids attached at the C-terminal end. What is a plausible explanation for its origin? arose from failure to splice out an intron? the ß globin has several extra Is it likely that Hb Constant amino Spring

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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**Mutation and Protein Analysis Problems**

1. Geneticists interested in human hemoglobins have found a very large number of mutations. Some of these mutant proteins are of normal size, while others are short due to deletions or nonsense mutations. The first example, often named Hb Constant Spring, is where the globin has several extra amino acids attached at the C-terminal end. What is a plausible explanation for its origin? Is it likely that Hb Constant Spring arose from failure to splice out an intron?

Name: [Student's Name]
Transcribed Image Text:**Mutation and Protein Analysis Problems** 1. Geneticists interested in human hemoglobins have found a very large number of mutations. Some of these mutant proteins are of normal size, while others are short due to deletions or nonsense mutations. The first example, often named Hb Constant Spring, is where the globin has several extra amino acids attached at the C-terminal end. What is a plausible explanation for its origin? Is it likely that Hb Constant Spring arose from failure to splice out an intron? Name: [Student's Name]
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