Mistakes made by DNA polymerase are corrected either by proofreading mechanisms during DNA replication or by DNA repair systems that operate after replication is complete. The overall rate of errors in DNA replication is about 1 × 10−10, that is, one error in 10 million base pairs. RNA polymerase also has some proofreading capability, but the overall error rate for transcription is significantly higher (1 × 10−4) or one error in each 10,000 nucleotides). Why can organisms tolerate higher error rates for transcription than for DNA replication?

Q: Which RE’s from table below have a 5’ overhang? Which ones have a 3’ Overhang?   AccI GT^CGAC…

A: Restriction enzymes are the specific enzymes that recognize and cut at specific sites on nucleotide…

Q: he Meselson and Stahl experiment provided conclusive evidence for the semiconservative replication…

A: The objective of the question is to understand the expected results of the Meselson and Stahl…

Q: functions. The structure that provides high processivity (processivity factor) is represented by the…

A: Letter A denotes core polymerase enzyme B denotes tau protein C denotes gamma clamp loader D denotes…

Q: DNA polymerase I DNA polymerase II DNA ligase Primase RNA primer 5' Lagging strand 3' 3' Okazaki…

A: The process of copying of double stranded DNA by the application of several Enzymes and proteins…

Q: An investigator obtains a bacterial temperature-sensitive mutation that affects a step in the…

A: Every DNA molecule is twisted into a ladder form known as a "double helix." The backbone of the DNA…

Q: ents the biochemical reaction that occurs durin

A: Introduction:-  DNA synthesis is the biological process by which a deoxyribonucleic acid(DNA)…

Q: Which of the following statements is TRUE?   Synthesis of the lagging strand requires more DNA…

A: DNA replication is a process in which it is done to copy the cell DNA. * This process is…

Q: The purpose of DNA gyrase in replication is: to relieve positive supercoiling induced by unwinding…

A: Introduction: The process of DNA replication involves the production of an exact copy of genetic…

Q: 1 MSH2 MSH6 Template strand 5' A 3' Newly synthesized daughter strand MLH1 endonuclease, PMS2 2 DNA…

A: The mismatch excision-repair pathway corrects errors introduced during replication Step 1: A complex…

Q: DNA polymerases have exonuclease activity that hydrolyzes DNA in the 3′ to 5′ direction. When an…

A: DNA POLYMERASE: DNA polymerase is an enzyme that plays a key role in the replication of DNA, the…

Q: Fill in the blank spaces below with the most appropriate terms. The word bank is not provided. DNA…

A: During cell division DNA makes a copy of itself and this process is called DNA replication. In this…

Q: Describe an experimental approach to determining the processivity of a DNA polymerase (that is, the…

A: The processivity is defined as the degree of the addition of an average number of nucleotides prior…

Q: List two possible reasons why a mistake during the process of replication is more of a catastrophe…

A: When a DNA (deoxyribonucleic acid) molecule (double-stranded) gets copied into two new similar…

Q: DNA Polymerase Holoenzyme Il is represented below. It consists of several domains with distinct…

A: At the replication fork, DNA polymerase III holoenzyme (Pol III HE) works with the helicase and…

Q: Spontaneous oxidative deamination of guanine produces the base xanthine (see figure, which also…

A: As per the Watson-Crick model of the DNA double helix:DNA is made up of two strands of…

Q: In 1958, Meselson and Stahl conducted an experiment to determine which of the three proposed methods…

A: Three important experiments contributed to our current understanding of DNA structure and function:…

Q: Which of the following mechanisms does not contribute to reducing the overall in vivo mutation rate…

A: Any alteration to an organism's genome's DNA sequence is referred to as a mutation. The genetic…

Q: In Polymerase Chain Reaction (PCR), the temperature is one of the most important parameters that…

A: Note:  As per the guidelines, the first question has been solved here. Please post the other…

Q: Which of the following processes of genetic information flow can occur under laboratory conditions,…

A: The DNA (deoxyribonucleic acid) is the double-stranded molecule which is the genetic material in…

Q: What is an advantage and a disadvantage of this repair system?

A: DNA is the genetic material that carries genetic information in the form of coded nucleotide…

Q: An investigator obtalns a bacterial temperature-sensitive mutation that affects a step in the…

A: DNA (deoxyribonucleic acid) was discovered by Friedrich Miescher. Nucleotides are the structural…

Q: DNA polymerase requires both a template, to be copied, and a primer, which provides a 3′ hydroxyl…

A: DNA polymerase is a main enzyme for DNA replication.. The two main requirements for working of  DNA…

Q: An Investigator obtains a bacterial temperature-sensitive mutation that affects a step in the…

A: Most of the replication enzymes are proteinaceous in nature. The structure of a protein is formed by…

Q: How is DNA copied with leading and lagging strands? Please use these terms in a summary: Helicase…

A: DNA is the molecule which comprises of two polynucleotide chains that wound around each other for…

Q: What is a true statement about the leading and lagging strands during DNA synthesis? The leading…

A: Ans : Correct statement for the above question is - The lagging strand is created due to DNA…

Q: What is the role of alcohol in extracting DNA? O DNA is a polar molecule with an overall negative…

A: DNA is deoxyribonucleic acid, is a nucleic acid it is deoxy in the 2nd Carbon that makes DNA more…

Q: DNA mismatch repair enzymes preferentially repair bases on the newly synthesized DNA strand, using…

A: DNA mismatch repair enzymes play an important role in maintaining the accuracy of DNA replication.…

Q: Explain why the absorption of UV light by double-stranded DNA increases (the hyperchromic effect)…

A: Hyperchromicity is the effect of the increase in the absorbance of the molecule.

Q: ven though the eukaryotic genome is thousands of times larger than the prokaryotic genome, DNA…

A: Answer: EUKARYOTIC GENOME is more complex and larger than PROKARYOTIC GENOME beacuse prokaryotic…

Q: Single-strand binding proteins keep the two parental strands of DNA separated from each other until…

A: Deoxyribonucleic acid or DNA is the genetic material that is passed on from the parents to the…

Q: Collisions between DNA polymerase and a slower-moving RNA polymerase using the same template strand…

A: DNA is a double-stranded molecule. During its replication, two-parent strands unwind and each strand…

Genome annotation

The technique of linking biological information to genome sequences is termed genome annotation. Gene annotation is the method of identifying gene locations and coding sections. It helps us understand what these genes are doing in the body through establishing structural characteristics and linking them to the actions of various proteins.