Imagine that a single mutation to chymotrypsin destroys the specificity pocket by introducing a lare R-group that blocks off the opening to the pocket, so that no part of the substratecan enter the pocket. Think about what we know about what the specificity pocket does. If the mutation has only one of the impacts listed below,which one of the following is it, most likely, based on our coverage? Greately increases Kcat. Greately decreases Km. Greately increases Km. Greately decreases Kcat.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
Imagine that a single mutation to chymotrypsin destroys the specificity pocket by introducing a lare R-group that blocks off the opening to the pocket, so that no part of the substratecan enter the pocket.
Think about what we know about what the specificity pocket does. If the mutation has only one of the impacts listed below,which one of the following is it, most likely, based on our coverage?
- Greately increases Kcat.
- Greately decreases Km.
- Greately increases Km.
- Greately decreases Kcat.
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