Scientists are currently screening a chemical library of small molecules for inhibitors of bioluminescence in response to high cell density in V. fischeri.The small molecules were chosen for their potentialability to bind LuxR.a. How could a molecule that binds LuxR preventbioluminescence?b. Hundreds of different bacterial species use quorumsensing mechanisms similar to that of V. fischeri andencode proteins similar to LuxI and LuxR. In lightof this information, why do you think scientists wantto identify the molecule described in part (a)?
Genetic Recombination
Recombination is crucial to this process because it allows genes to be reassorted into diverse combinations. Genetic recombination is the process of combining genetic components from two different origins into a single unit. In prokaryotes, genetic recombination takes place by the unilateral transfer of deoxyribonucleic acid. It includes transduction, transformation, and conjugation. The genetic exchange occurring between homologous deoxyribonucleic acid sequences (DNA) from two different sources is termed general recombination. For this to happen, an identical sequence of the two recombining molecules is required. The process of genetic exchange which occurs in eukaryotes during sexual reproduction such as meiosis is an example of this type of genetic recombination.
Microbial Genetics
Genes are the functional units of heredity. They transfer characteristic information from parents to the offspring.
Scientists are currently screening a chemical library of small molecules for inhibitors of bioluminescence in response to high cell density in V. fischeri.
The small molecules were chosen for their potential
ability to bind LuxR.
a. How could a molecule that binds LuxR prevent
bioluminescence?
b. Hundreds of different bacterial species use quorum
sensing mechanisms similar to that of V. fischeri and
encode proteins similar to LuxI and LuxR. In light
of this information, why do you think scientists want
to identify the molecule described in part (a)?
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