The complete absence of one or more teeth (tooth agenesis) is a common trait in humans—indeed, more than 20% of humans lack one or more of their third molars. However, more severe tooth agenesis, defined as the absence of six or more teeth, is less common and is frequently an inherited condition. L. Lammi and colleagues examined tooth agenesis in the Finnish family shown in the pedigree below. II49.II34 5IV2[Source: L. Lammi. 2004. American Journal of Human Genetics74:1043–1050.]a. What is the most likely mode of inheritance for tooth agenesis in thisfamily? Explain your reasoning.b. Are the two sets of twins in this family monozygotic or dizygotic twins?What is the basis of your answer?c. If IV-2 married a man who had a full set of teeth, what is the probabilitythat their child would have tooth agenesis?d. If III-2 and III-7 married and had a child, what is the probability thattheir child would have tooth agenesis?

Tooth agenesis is a dental anomaly that affects approximately 20% of the population's wisdom tooth.…

Answered: II 4 9. II 3 4 5 IV 2 [Source: L.…

Human Anatomy & Physiology (11th Edition)

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Author:Elaine N. Marieb, Katja N. Hoehn

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The complete absence of one or more teeth (tooth agenesis) is a common
trait in humans—indeed, more than 20% of humans lack one or more of
their third molars. However, more severe tooth agenesis, defined as the
absence of six or more teeth, is less common and is frequently an
inherited condition. L. Lammi and colleagues examined tooth agenesis
in the Finnish family shown in the pedigree below.

II
4
9.
II
3
4 5
IV
2
[Source: L. Lammi. 2004. American Journal of Human Genetics
74:1043–1050.]
a. What is the most likely mode of inheritance for tooth agenesis in this
family? Explain your reasoning.
b. Are the two sets of twins in this family monozygotic or dizygotic twins?
What is the basis of your answer?
c. If IV-2 married a man who had a full set of teeth, what is the probability
that their child would have tooth agenesis?
d. If III-2 and III-7 married and had a child, what is the probability that
their child would have tooth agenesis?

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