II 3 II 3 4 5 6 IV 2 3 4 5 6 7 1 2 3 [Source: D. Stambolian, R. A. Lewis, K. Buetow, A. Bond, and R. Nussbaum. 1990. American Journal of Human Genetics 47:15.] 4 1. On the basis of this pedigree, what do you think is the most likely mode of inheritance for Nance-Horan syndrome? o. If couple III-7 and III-8 have another child, what is the probability that he child will have Nance-Horan syndrome? . If III-2 and III-7 were to mate, what is the probability that one of their children would have Nance-Horan syndrome? %3D

II 3 II 3 4 5 6 IV 2 3 4 5 6 7 1 2 3 [Source: D. Stambolian, R. A. Lewis, K. Buetow, A. Bond, and R. Nussbaum. 1990. American Journal of Human Genetics 47:15.] 4 1. On the basis of this pedigree, what do you think is the most likely mode of inheritance for Nance-Horan syndrome? o. If couple III-7 and III-8 have another child, what is the probability that he child will have Nance-Horan syndrome? . If III-2 and III-7 were to mate, what is the probability that one of their children would have Nance-Horan syndrome? %3D

Name: The following pedigree illustrates the inheritance of Nance–Horan synd
Uploaded: 2024-03-20T06:43:04.000Z
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Description: The following pedigree illustrates the inheritance of Nance–Horan syndrome, a rare genetic condition in which affected people have cataracts and abnormally shaped teeth. II3II345 6IV23 45 6 71 2 3[Source: D. Stambolian, R. A. Lewis, K. Buetow, A. Bon

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter4: Pedigree Analysis In Human Genetics

Section: Chapter Questions

Problem 10QP: A proband female with an unidentified disease seeks the advice of a genetic counselor before...

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BIU A- == 三E 12 - Match each of the following examples to the appropriate type of non-Mendelian inheritance. 1. A homozygous recessive genotype for the gene that encodes phenylalanine hydroxylase (which breaks down the amino acid phenylalanine) causes lighter skin color, a musty odor, differences in intellectual development, and seizures. 2. In pea plants, alleles of Gene W control flower color, with the dominant allele (W) leading to purple flower.color, and the recessive allele (w) leading to white flower color. Usually, a genotype of WW or Ww leads to purple flowers. However, when Gene C is homozygous recessive, WW or Ww plants always have white flowers. 3. In mallard ducks, feather coloring is controlled by Gene F. A dominant allele (F) leads to green head feathers, while a recessive allele (f) leads to brown head feathers. In male mallards, inheritance of one or more F alleles always leads to the green head feather trait. But female mallards always have brown head feathers,…
The following pedigree illustrates the inheritance of ringed hair, a condition in which each hair is differentiated into light and dark zones. What mode or modes of inheritance are possible for the ringed-hair trait in this family?
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What is the mode of inheritance of this pedigree and why?
For the following problems, please choose from the following modes of inheritance: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive 8080 50 OTO ㅁㅇㅇㅁ I. What is the most likely mode of inheritance portrayed in the pedigree above?
26. The trait represented in the following pedigree is expressed only in the males of the family. Is the trait Y linked? Why or why not? If you believe that the trait is not Y linked, propose an alternative explanation for its inheritance. 1 2 II 3 6 II I 2 3 4 5 6 7 8 IV 1 2 Pierce, Genetics: A Conceptual Approach, 7e © 2020 W. H. Freeman and Company
Please draw it out so I understand how it's suppose to be drawn
1. The pedigree below shows the incidence of rare, autosomal dominant disorder called Ehlers-Danlos disease. The pedigree covers three generations of a particular family and also shows individual genotypes at a potential marker locus (M). a) Indicate the phase of all gen II and III individuals. DdM1M3 ddM2M6 II DDM3M6 ddM4M5 III DdMзM4 DdMЗМ5 DDM3M4 ddM3M5 DDM3M4 ddM5M6 DDM3M4 ddM4M6 ddM5M6 ddM5M6 b) Which, if any, of the gen III individuals are recombinants? c) Calculate the LOD score as a test of physical linkage between the marker (M) and the disease locus. d) What do you conclude about linkage between D and M?
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F1 result Wild-type Mutant P: Wild type female x mutant male 0 258 P: wild type male x mutant female 0 193 F2 result Wild type Mutant F1 male x F1 female 268 205 what is the most likely mode of inheritance? 1. What is the Chi-square value for F2?
6) For the pedigree shown below, answer the following questions. I II III a) What type of inheritance is shown? Explain how you know. b) The genotype of individual I -2 is The genotype of individual II -1 is
1 III IV Lactose tolerant female Lactose intolerant female 3 Recessive 3 Recessive 6 Lactose tolerant male Lactose intolerant male Dominant 8 9 10 7 8 Dominant Figure 2. Pedigree of Family A. (Adapted from a figure in Enattah, N. S., et al. 2002 Nature Genetics 30: 233-237.) 1. Based on the pedigree above, which of the following terms are appropriate for describing the inheritance of the lactose-intolerance trait (filled-in symbols)? Check all that apply. X-linked Family A 9 11 ? Unknown phenotype Deceased X-linked 2. Which of the following terms are appropriate for describing the inheritance of the lactose-tolerance trait (empty symbols)? Mark all that apply. Autosomal Autosomal You decide you need more data to find out if your model for inheritance of lactose intolerance holds up. You examine three additional pedigrees from the Finnish study.