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How does complement promote the immune response? Describe three ways
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- What is complement? What are the actions of complement? What are antibodies? What are the actions of antibodies? What is an APC? How do APCs function during an immune response?List and describe the three outcomes of complement activation.Describe how the complement system works, and list 3 effects that complement activation has.
- Describe the roles that phagocytic and nonphagocytic cells and plasma proteins such as complement and interferon play in innate immunity?Which of the following best describes the type of immunity acquired in the following example? Example: An infant receives antibodies from the mother through breastfeeding. A) passive, natural B) passive, artificial active, natural active, artificial Question 33 What caused COVID-19 to be re-ciassif ed from an epidemic to a pandemic?What is MHC? List the specific cells that have MHC presentation and describe their role in the immune response.
- Describe the complement system. Is the order ofprotein interactions important? Why or why not?Identify the components of the mannose-binding lectinpathway for complement activation.Which of the following is true about complement? Check all that apply. Three pathways of complement, where classical and alternative, are activated by antibodies and lectin by spontaneous hydrolysis of C3 Complement pathways are activated in response to infections and involved in opsonization, phagocytosis and lysis of microbes The"b" subunit of complement such as C3b or C5b is deposited on the microbes, whereas the "a" subunit, C3a or C5a recruits phagocytic cells to the site of infection and promotes inflammation Alternative pathway is activated immediately due to presence of C3b because of spontaneous hydrolysis of C3, whereas classical pathways in several days after secretion of pathogen-specific antibodies Seven complement(C) proteins are made by liver and C5 is found in abundanceA 40-year-old man with a complement deficiency agrees to participate in a clinical study of immune mechanisms. The subject is unable to activate the complement system by the classical pathway, but he can activate the complement system by the alternate pathway. Deletion of which of the following components is consistent with these findings? A) C2 B) C3 C) C5 D) C8 E) Factor B F) Factor D OG) Factor H OH) von Willebrand factor
- What are the principle components and functions of innate and adaptive (Humoral and cell-mediated) immunity? describe in 100 wordsThe complement system supplements the inflammatory response by directly killing microorganisms. Describe the life cycle of complement proteins, from their synthesis in the liver to their activity in the site of an infection.