Glycogen phosphorylase catalyzes the inorganic phosphate-mediated removal of glucose from glycogen (glycogen, to glycogenn-1), allowing the production of glucose 1- phopshate. The DGº for this reaction is +1.6 kJ/mol and R=8.31 J.mol1.K1 (Hint: The removal of glucose units from glycogen does not change the glycogen concentration at equilibrium or physiological conditions). 1- Write down the net equation of the reaction. 2- Calculate the [Pi]/[glucose 1-phosphate] ratio at the equilibrium at 25°C. 3- The ratio [Pi]/[glucose 1-phosphate] of this reaction is equal to 100 in the skeletal muscle under physiological conditions. 3a- Calculate the DG' of the reaction under physiological conditions at 25°C. 3b- What is the direction of this reaction under physiological conditions in the skeletal muscle?.
Glycogen phosphorylase catalyzes the inorganic phosphate-mediated removal of glucose from glycogen (glycogen, to glycogenn-1), allowing the production of glucose 1- phopshate. The DGº for this reaction is +1.6 kJ/mol and R=8.31 J.mol1.K1 (Hint: The removal of glucose units from glycogen does not change the glycogen concentration at equilibrium or physiological conditions). 1- Write down the net equation of the reaction. 2- Calculate the [Pi]/[glucose 1-phosphate] ratio at the equilibrium at 25°C. 3- The ratio [Pi]/[glucose 1-phosphate] of this reaction is equal to 100 in the skeletal muscle under physiological conditions. 3a- Calculate the DG' of the reaction under physiological conditions at 25°C. 3b- What is the direction of this reaction under physiological conditions in the skeletal muscle?.
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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![Glycogen phosphorylase catalyzes the inorganic phosphate-mediated removal of glucose from glycogen (glycogen, to glycogenn-1), allowing the production of glucose 1-
phopshate. The DG° for this reaction is +1.6 kJ/mol and R=8.31 J.mol1.K1 (Hint: The removal of glucose units from glycogen does not change the glycogen concentration at
equilibrium or physiological conditions).
1- Write down the net equation of the reaction.
2- Calculate the [Pi]/[glucose 1-phosphate] ratio at the equilibrium at 25°C.
3- The ratio [Pi]/[glucose 1-phosphate] of this reaction is equal to 100 in the skeletal muscle under physiological conditions.
3a- Calculate the DG' of the reaction under physiological conditions at 25°C.
3b- What is the direction of this reaction under physiological conditions in the skeletal muscle?.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fcb7ce319-01ff-4971-bd9e-7eded90e46e1%2F3c62d358-de01-4748-aa51-8c5e4d28f8a5%2F2qwnzr_processed.png&w=3840&q=75)
Transcribed Image Text:Glycogen phosphorylase catalyzes the inorganic phosphate-mediated removal of glucose from glycogen (glycogen, to glycogenn-1), allowing the production of glucose 1-
phopshate. The DG° for this reaction is +1.6 kJ/mol and R=8.31 J.mol1.K1 (Hint: The removal of glucose units from glycogen does not change the glycogen concentration at
equilibrium or physiological conditions).
1- Write down the net equation of the reaction.
2- Calculate the [Pi]/[glucose 1-phosphate] ratio at the equilibrium at 25°C.
3- The ratio [Pi]/[glucose 1-phosphate] of this reaction is equal to 100 in the skeletal muscle under physiological conditions.
3a- Calculate the DG' of the reaction under physiological conditions at 25°C.
3b- What is the direction of this reaction under physiological conditions in the skeletal muscle?.
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