How many ATP are produced from the complete degradation of 1,3-bisphosphoglycerate? the complete degradation of ONE glucose using the malate-aspartate shuttle as your guide. HexokinasePhosphofructokinase2xGlyceraldehyde-3-P Dehydrogenase2xPhosphoglyerate Kinase2xPyruvate Kinase2xPyruvate Dehydrogenase Complex2xlsocitrate Dehydrogenase2xa-Ketoglutarate Dehydrogenase2xSuccinyl-CoA Synthetase2xSuccinate Dehydrogenase2xMalate Dehydrogenase-1 ATP (Phosphorylation)-1 ATP (Phosphorylation)+2 NADHoytosolic = 5 ATP (Malate-Aspartate)+2 ATP (Substrate Level Phosph.)+2 ATP (Substrate Level Phosph.)+2 NADH = 5 ATP+2 NADH = 5 ATP+2 NADH = 5 ATP= -1 ATP=-2 ATP= 3 ATP= 5 ATP= 7 ATP= 12 ATP= 17 ATP= 22 ATP= 24 ATP= 27 ATP= 32 ATP+2 GTP = 2 ATP (Substrate Level Phosph.)+2 FADH2 = 3 ATP+2 NADH = 5 ATP

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Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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How many ATP are produced from the complete degradation of 1,3-bisphosphoglycerate? the complete degradation of ONE glucose using the malate-aspartate shuttle as your guide.

Hexokinase
Phosphofructokinase
2xGlyceraldehyde-3-P Dehydrogenase
2xPhosphoglyerate Kinase
2xPyruvate Kinase
2xPyruvate Dehydrogenase Complex
2xlsocitrate Dehydrogenase
2xa-Ketoglutarate Dehydrogenase
2xSuccinyl-CoA Synthetase
2xSuccinate Dehydrogenase
2xMalate Dehydrogenase
-1 ATP (Phosphorylation)
-1 ATP (Phosphorylation)
+2 NADHoytosolic = 5 ATP (Malate-Aspartate)
+2 ATP (Substrate Level Phosph.)
+2 ATP (Substrate Level Phosph.)
+2 NADH = 5 ATP
+2 NADH = 5 ATP
+2 NADH = 5 ATP
= -1 ATP
=-2 ATP
= 3 ATP
= 5 ATP
= 7 ATP
= 12 ATP
= 17 ATP
= 22 ATP
= 24 ATP
= 27 ATP
= 32 ATP
+2 GTP = 2 ATP (Substrate Level Phosph.)
+2 FADH2 = 3 ATP
+2 NADH = 5 ATP

Expert Solution

Step 1

One molecule of glucose gives two molecule of pyruvate, which enters TCA cycle for complete oxidation.

1,3-bisphosphoglycerate is an intermediate of glycolysis.

1,3-bisphosphoglycerate is converted to one molecule of pyruvate. This pyruvate enters TCA cycle for further complete oxidation.

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