During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced from the breakdown of glucose is converted into lactate. High lactate levels can lead to acidity in the muscle cells as some of the lactate hydrolyzes to lactic acid. The dissociation of lactic acid to lactate is shown in the reaction. Lactic acid has a pK, of 3.86. + H+ OH OH OH Lactic acid Lactate A solution containing a mixture of lactic acid and lactate was found to have a pH of 3.56. Calculate the ratio of the lactate concentration to the lactic acid concentration in this solution. [lactate] [lactic acid] What fraction of the lactic acid/lactate mixture is lactic acid?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
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Chapter1: Biochemistry: An Evolving Science
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During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced
from the breakdown of glucose is converted into lactate. High lactate levels can lead to acidity in the muscle cells as some of the
lactate hydrolyzes to lactic acid.
The dissociation of lactic acid to lactate is shown in the reaction. Lactic acid has a pK₂ of 3.86.
+ H+
O™
OH
OH
OH
Lactic acid
Lactate
A solution containing a mixture of lactic acid and lactate was found to have a pH of 3.56. Calculate the ratio of the lactate
concentration to the lactic acid concentration in this solution.
[lactate]
[lactic acid]
What fraction of the lactic acid/lactate mixture is lactic acid?
Transcribed Image Text:During exercise when the body lacks an adequate supply of oxygen to support energy production, the pyruvate that is produced from the breakdown of glucose is converted into lactate. High lactate levels can lead to acidity in the muscle cells as some of the lactate hydrolyzes to lactic acid. The dissociation of lactic acid to lactate is shown in the reaction. Lactic acid has a pK₂ of 3.86. + H+ O™ OH OH OH Lactic acid Lactate A solution containing a mixture of lactic acid and lactate was found to have a pH of 3.56. Calculate the ratio of the lactate concentration to the lactic acid concentration in this solution. [lactate] [lactic acid] What fraction of the lactic acid/lactate mixture is lactic acid?
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