Please help fill out the metabolic Pathway table of Gluconeogenesis and Tricarboxylic by listing its enzymes and functions Gluconeogenesis (work only on the enzymes that are not shared with the glycolytic pathway)AGEnzymeReaction(kJ/mol)ECTricarboxylic Acid Cycle (include pyruvate dehydrogenase complex) = KREBSEnzymeECPyruvate dehydrogenase complex 1.2.4.1ReactionAG(kJ/mol)Pyruvate Acetyl-S-CoA + -33.4CO₂→→CofactorsRegulationCofactorsLipoic acid, thiaminepyrophosphate, FAD, NAD, S-COACoenzyme A.RegulationInhibited by NADH+H, ATP, acetyl-Stimulated by NAD+, AMP andcoenzyme ANotesNotesPDH deficiency: ataxia, poor muscletone, high lactate, etc. (GHR, 2012)

Gluconeogenesis is the metabolic pathway responsible for the synthesis of glucose from…

Gluconeogenesis (work only on the enzymes that are not shared with the glycolytic pathway) AG (kJ/mol) Enzyme EC Reaction Tricarboxylic Acid Cycle (include pyruvate dehydrogenase complex) = KREBS EC Enzyme Pyruvate dehydrogenase complex 1.2.4.1 AG (kJ/mol) Pyruvate Acetyl-S-CoA +-33.4 CO₂ Reaction Cofactors Cofactors Lipoic acid, thiamine pyrophosphate, FAD, NAD, S-CoA. Coenzyme A. Regulation Regulation Inhibited by NADH + H, ATP, acetyl- Stimulated by NAD+, AMP and coenzyme A Notes Notes PDH deficiency: ataxia, poor muscle tone, high lactate, etc. (GHR, 2012)

Gluconeogenesis (work only on the enzymes that are not shared with the glycolytic pathway) AG (kJ/mol) Enzyme EC Reaction Tricarboxylic Acid Cycle (include pyruvate dehydrogenase complex) = KREBS EC Enzyme Pyruvate dehydrogenase complex 1.2.4.1 AG (kJ/mol) Pyruvate Acetyl-S-CoA +-33.4 CO₂ Reaction Cofactors Cofactors Lipoic acid, thiamine pyrophosphate, FAD, NAD, S-CoA. Coenzyme A. Regulation Regulation Inhibited by NADH + H, ATP, acetyl- Stimulated by NAD+, AMP and coenzyme A Notes Notes PDH deficiency: ataxia, poor muscle tone, high lactate, etc. (GHR, 2012)

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Please help fill out the metabolic Pathway table of Gluconeogenesis and Tricarboxylic by listing its enzymes and functions

Gluconeogenesis (work only on the enzymes that are not shared with the glycolytic pathway)
AG
Enzyme
Reaction
(kJ/mol)
EC
Tricarboxylic Acid Cycle (include pyruvate dehydrogenase complex) = KREBS
Enzyme
EC
Pyruvate dehydrogenase complex 1.2.4.1
Reaction
AG
(kJ/mol)
Pyruvate Acetyl-S-CoA + -33.4
CO₂
→
→
Cofactors
Regulation
Cofactors
Lipoic acid, thiamine
pyrophosphate, FAD, NAD, S-COA
Coenzyme A.
Regulation
Inhibited by NADH+H, ATP, acetyl-
Stimulated by NAD+, AMP and
coenzyme A
Notes
Notes
PDH deficiency: ataxia, poor muscle
tone, high lactate, etc. (GHR, 2012)

Chemical pathways by which living things function, especially those that provide cellular energy, such as the transformation of energy from food into the energy of ATP. Metabolism also focuses on chemical pathways involving the synthesis of new biomolecules and the elimination of waste.

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