The pentose phosphate pathway provides a number of critical functions including ["production of ribose-5-phosphate", "production of NADH"] that is vital for ["synthesis of nucleotides and coenzymes", "oxidative phosphorylation"] . This pathway is divided into oxidative and non-oxidative steps. The latter steps ["are involved in the conversion of various sugar phopshates, so called ["carbon shuffle reactions"", "are directly involved in NADPH production"] . If ["NADP+", "NAD+"] levels are high, flux through the pentose phosphate pathway is promoted by allosteric regulation of glucose-6-phosphate dehydrogenase. If reducing equivalents derived form the pentose phosphate pathway are high, glucose-6-phosphate is directed toward ["a phosphatase and then export from the cell", "glycolysis"]
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The pentose phosphate pathway provides a number of critical functions including ["production of ribose-5-phosphate", "production of NADH"] that is vital for ["synthesis of
This pathway is divided into oxidative and non-oxidative steps. The latter steps ["are involved in the conversion of various sugar phopshates, so called ["carbon shuffle reactions"", "are directly involved in NADPH production"] .
If ["NADP+", "NAD+"] levels are high, flux through the pentose phosphate pathway is promoted by allosteric regulation of glucose-6-phosphate dehydrogenase. If reducing equivalents derived form the pentose phosphate pathway are high, glucose-6-phosphate is directed toward ["a phosphatase and then export from the cell", "glycolysis"] .
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