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Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate carboxylase, to be the primary target for the regulation of gluconeogenesis at the level of control of enzyme synthesis? Match the words in the left column to the appropriate blanks in the sentences on the right. fructose-1,6-bisphosphate pyruvate 3-phosphoglycerate increasing reducing glycolytic pathway forward acetaldehyde lactate phosphoenolpyruvate oxaloacetate citric acid cycle back glyceraldehyde- 3-phosphate Firstly, pyruvate carboxylase converts which can participate in the gluconeogenesis pathway, and also plays an additional metabolic role in aiding the entry of intermediates into the Hence, it makes sense for phosphoenolpyruvate carboxykinase (PEPCK) to catalyze the conversion of gluconeogenesis pathway thereby to to Thirdly, PEPCK action results in the formation of amino acids and their subsequent entry into the citric acid cycle. Reset Help pyruvate carboxylase. Secondly, PEPCK aids the formation of dihydroxyacetone phosphate and can then participate in the synthesis of fatty acids/steroids. to push the the metabolic regulatory load on which , which aids in the synthesis of

Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate carboxylase, to be the primary target for the regulation of gluconeogenesis at the level of control of enzyme synthesis? Match the words in the left column to the appropriate blanks in the sentences on the right. fructose-1,6-bisphosphate pyruvate 3-phosphoglycerate increasing reducing glycolytic pathway forward acetaldehyde lactate phosphoenolpyruvate oxaloacetate citric acid cycle back glyceraldehyde- 3-phosphate Firstly, pyruvate carboxylase converts which can participate in the gluconeogenesis pathway, and also plays an additional metabolic role in aiding the entry of intermediates into the Hence, it makes sense for phosphoenolpyruvate carboxykinase (PEPCK) to catalyze the conversion of gluconeogenesis pathway thereby to to Thirdly, PEPCK action results in the formation of amino acids and their subsequent entry into the citric acid cycle. Reset Help pyruvate carboxylase. Secondly, PEPCK aids the formation of dihydroxyacetone phosphate and can then participate in the synthesis of fatty acids/steroids. to push the the metabolic regulatory load on which , which aids in the synthesis of

Biochemistry
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate carboxylase, to be the primary target for the regulation of gluconeogenesis at the level of control of enzyme synthesis? Match the words in the left column to the appropriate blanks in the sentences on the right. fructose-1,6-bisphosphate pyruvate 3-phosphoglycerate increasing reducing glycolytic pathway forward acetaldehyde lactate phosphoenolpyruvate oxaloacetate citric acid cycle back glyceraldehyde- 3-phosphate Firstly, pyruvate carboxylase converts which can participate in the gluconeogenesis pathway, and also plays an additional metabolic role in aiding the entry of intermediates into the Hence, it makes sense for phosphoenolpyruvate carboxykinase (PEPCK) to catalyze the conversion of gluconeogenesis pathway , thereby pyruvate carboxylase. to to Thirdly, PEPCK action results in the formation of amino acids and their subsequent entry into the citric acid cycle. Reset Help to push the the metabolic regulatory load on Secondly, PEPCK aids the formation of dihydroxyacetone phosphate and can then participate in the synthesis of fatty acids/steroids. which , which aids in the synthesis of
Transcribed Image Text:Why does it make good metabolic sense for phosphoenolpyruvate carboxykinase, rather than pyruvate carboxylase, to be the primary target for the regulation of gluconeogenesis at the level of control of enzyme synthesis? Match the words in the left column to the appropriate blanks in the sentences on the right. fructose-1,6-bisphosphate pyruvate 3-phosphoglycerate increasing reducing glycolytic pathway forward acetaldehyde lactate phosphoenolpyruvate oxaloacetate citric acid cycle back glyceraldehyde- 3-phosphate Firstly, pyruvate carboxylase converts which can participate in the gluconeogenesis pathway, and also plays an additional metabolic role in aiding the entry of intermediates into the Hence, it makes sense for phosphoenolpyruvate carboxykinase (PEPCK) to catalyze the conversion of gluconeogenesis pathway , thereby pyruvate carboxylase. to to Thirdly, PEPCK action results in the formation of amino acids and their subsequent entry into the citric acid cycle. Reset Help to push the the metabolic regulatory load on Secondly, PEPCK aids the formation of dihydroxyacetone phosphate and can then participate in the synthesis of fatty acids/steroids. which , which aids in the synthesis of
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