Exercise 1: Albinism is a hereditary deficiency characterized by the absence of pigmentation in the skin, eyes, and hair, due to the absence of a black pigment: the melanin. Tyrosinase is an enzyme implicated in the biosynthesis of this pigment. The gene coding for tyrosinase exists in different alleles. We consider only 2 alleles: allele A coding for the active tyrosinase responsible for the synthesis of melanin, and allele B coding for the inactive tyrosinase which doesn't allow the synthesis of Albinism melanin. The document below represents a partial sequence of a strand of the 2 alleles A and B. Number of triplet 80 81 82 83 84 85 Allele A TGC САА CGA TCC ТАТ СТТ Allele B TGC САА САА ТСС ТАТ 1. 1.1. Compare the sequences of the 2 alleles coding for tyrosinase. 1.2.What can you conclude concerning the position and the type of the mutation that took place? hook

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Exercise 1:
Albinism is a hereditary deficiency characterized by the absence of pigmentation in the skin, eyes, and hair,
due to the absence of a black pigment: the melanin.
Tyrosinase is an enzyme implicated in the biosynthesis of this pigment. The gene coding for tyrosinase
exists in different alleles. We consider only 2 alleles: allele A coding for the active tyrosinase responsible for
the synthesis of melanin, and allele B coding for the inactive tyrosinase which doesn't allow the synthesis of
Albinism
melanin.
The document below represents a partial sequence of a strand of the 2 alleles A and B.
Number
80
81
82
83
84
85
of triplet
Allele A
TGC
САА
CGA
ТСС
ТАТ
Allele B
TGC
CAA
САА
ТСС
ТАТ
...
1. 1.1. Compare the sequences of the 2 alleles coding for tyrosinase.
1.2.What can you conclude concerning the position and the type of the mutation that took
place?
shotos
Transcribed Image Text:Exercise 1: Albinism is a hereditary deficiency characterized by the absence of pigmentation in the skin, eyes, and hair, due to the absence of a black pigment: the melanin. Tyrosinase is an enzyme implicated in the biosynthesis of this pigment. The gene coding for tyrosinase exists in different alleles. We consider only 2 alleles: allele A coding for the active tyrosinase responsible for the synthesis of melanin, and allele B coding for the inactive tyrosinase which doesn't allow the synthesis of Albinism melanin. The document below represents a partial sequence of a strand of the 2 alleles A and B. Number 80 81 82 83 84 85 of triplet Allele A TGC САА CGA ТСС ТАТ Allele B TGC CAA САА ТСС ТАТ ... 1. 1.1. Compare the sequences of the 2 alleles coding for tyrosinase. 1.2.What can you conclude concerning the position and the type of the mutation that took place? shotos
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