Phenylketonuria (PKU) is a recessive disease (k); the normal ability to metabolize phenylalanine is dominant (K). A man and a woman with normal ability to metabolize phenylalanine are both heterozygous for this locus. a. What is the probability of this couple's first three children having the normal ability to metabolize phenylalanine, followed by two children with PKU? b. What is the probability of this couple having a family of four children consisting of two with PKU and two that are normal? c. What is the probability of this couple having a family with four children with either all having PKU or all being normal for phenylalanine metabolism?

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