diversity of receptors surface of B cells. 單選: A. Rearrangement of B cell receptor genes B. can ensure that a great can be generated on the Alternative splicing C. Antibody class switching D. Affinity maturation E. Somatic hypermutation

Q: T-cell receptor diversity is controlled by Select one: DNA recombination during prophase of meiosis…

A: T cells are the lymphocytes involved in adaptive immune responses. These cells have receptors for…

Q: Give 5 storage conditions of human normal immunoglobulin injection and why?

A: Human normal Immunoglobulin contains normal human immunoglobulin  , it replaced the  defficient…

Q: Identify the highlighted part of the antibody

A: An antibody can be defined as a defense protein. This protein is synthesized by the immune system of…

Q: On phagocytes and other cells, (?????) are receptors classified as part of the innate immune system…

A: The defense mechanism you were born with is called innate immunity, or nonspecific immunity. It…

Q: The reason why therapeutic anti-IgE is able to suppress allergic responses is that _____. a.…

A: The immune system is what protects your body from sicknesses and infections. It's the real system…

Q: All of the following have been observed in individuals deficient in either CD3δ or CD3ε except a.…

A: Answer: Introduction: CD3 means a cluster of differentiation is a complex of proteins and T- cell…

Q: All of the following are examples of how tumors or the microenvironment in which they develop…

A: Tumor cells are able to stimulate specific adaptive immune responses. However, most frequently these…

Q: Mutations occurring in B cells within the germinal center:

A: Germinal centers are sites within secondary lymphoid organs (lymph nodes and spleen)  -…

Q: What is the purpose of using a secondary antibody?

A: An antibody is a protein structure raised against a specific antigen. The antibody is denoted as Ab…

Q: HELP Immunology question

A: 1. Signal 1: 1. 4. Restriction on MHC Products: Specifically, this refers to the interaction that…

Q: in nucleated cells, the presentation of an antigen onto the surface of the cell is a normal process…

A: MHC-I consist of alpha chain and beta microglobulin and each have 45 kilodalton and 12 kilodalton…

Q: 29. T-cell dependent antigens can a. directly stimulate B cells to multiply and produce antibodies…

A: The correct answer is (c) restrict antibody formation. T-cell dependent antigens require the help of…

Q: Type II hypersensitivity reaction                                                  Type III…

A: Type IV hypersensitivity- Effector T cells specific for the sensitizing Ag Type II hypersensitivity…

Q: ADAM33 metalloproteinase inhibitors are sometimes co-administered with anti-tumor monoclonal…

A: A metalloproteinase is also known as metalloprotease. It is a type of protease enzyme that requires…

Q: Linked recognition is best described as _____. a. the delivery of the co-stimulatory signal by…

A: Humoral immunity involves the activation of lymphocytes (B and T lymphocytes) to provide defence…

Q: 6. The function of allelic exclusion is an increase in the ................of antibodies?.…

A: Introduction :- One allele of a gene is expressed while the other allele is silenced through the…

Q: Overcoming the carrier effect demonstrate which of the following immunological concepts:   A.…

A: The carrier effect is the finding that a secondary response to the hapten requires challenging the…

Q: During positive selection, if the selecting MHC molecule is class I, then a. gene expression of…

A: Positive selection refers to the event in which T cells become largely specified to develop…

Q: Dysfunctional repair of DNA double strand breaks often results in SCID because: thoose all that…

A: SCID stands for severe combined immunodeficiency disease.SCID is caused by adenosine deaminase (ADA)…

Q: A metabolically stressed epithelial cell expresses the protein MICits surface and then interacts…

A: NK cells are activated as an early event during an immune response and does not require the need for…

Q: Which of the following statements is false concerning T-cell development? a. γ and δ…

A: Thymus lymphocytes (T cells) are one of the major components of the adaptive immune system. There…

Q: Identify the highlighted part of the antibody

A: Immunity is the most talked-about term in this covid pandemic, it defines to be the body's mechanism…

Q: Barriers to using pig organs in human transplantation are _____. (Select all that apply.) a. the…

A: Graft rejection is one of the major problems in xenotransplantation. It is important to understand…

Q: It was mentioned to do Biocompatibility Testing to ensure the TPU scaffold and encapsulated beta…

A: Solution:- Biocompatibility testing assesses the compatibility of a material, like a TPU scaffold…

Q: Match the stage of B cell development with the rearrangement or expression of immunoglobulin genes.…

A: B cell development begins in the fetal liver and continues in the bone marrow throughout our lives.…

Q: To study the immune responses that provide protection against tumor growth in mice, some…

A: Cytokines are immunological molecules present in biological systems that are important for cell…

Q: 1. In central tolerance, 3 mechanisms deviate B cells away from making autoreactive antibody. Which…

A: These are multiple choice questions.

Q: Match the term with its complement. T-cell receptor 8-chain gene CD3 complex CD4 beta-2…

A: Major Histocompatibility Complex (MHC) MHC is the group of genes encoding for specufuc proteins that…

Q: During of B cell development, which of the following pairs is incorrect? Select one: a. IL-7: IL-7…

A: B cell development is a process in which B cells mature and differentiate from hematopoietic stem…

Q: Please outline the general steps you would take to test your hypothesis that SIN-47 works by…

A: Hypothesis: SIN-47 works by disrupting the interaction between LEK2 and JAK4.

Q: Multiple successive gene rearrangements at the immunoglobulin heavy-chain locus a. increase the…

A: One of the most remarkable features of the vertebrate immune system is its ability to respond to an…

Q: Shown below is the structure of Drug 1, that binds to the E. coli ribosome. Indicate whether each…

A: Since, you have asked multiple questions from multiple concepts, we have answered all 4 subparts of…

Q: 1. If an lg has a hydrophilic C terminus, then which of the following is true of the cell The cell…

A: Ig stands for immunoglobulins, a family of proteins that the immune system produces in reaction to…

Q: True or False: The class switch recombination of IgA antibodies is induced by TGF-beta or IL-21, and…

A: 3)It is a false statement.The IgA antibodies switching is done by T cell independent antigens and…

Q: In adoptive immunotherapy for melanoma, tumor-infiltrated lymphocytes(TILs) are expanded ex-vivo…

A: Melanoma is a serious and usually fatal kind of skin cancer that develops from melanocytes, the…

Q: Memory T cells _____. (Select all that apply.) a. must all be activated in secondary lymphoid…

A: Memory T cells are antigen-specific T cells that remain long-term after an infection has been…

Q: 18. You created a transgenic mouse in which all B cells express heavy and light chain of…

A: Transgenic mouse is a kind of mouse which is created artificially by genetic engineering that is by…

Q: 1 Each year's flu vaccine contains three flu strains - two A strains and one B strain - that can…

A: Immunization is the procedure through which a person develops resistance to an infectious disease.…

Q: B cells - A comparison of B and T cell maturation. List the locations and what is happening…

A: B and T cells, fundamental components of the adaptive immune system, undergo a structured maturation…

Q: Match the term in Column A with its correct description in Column B.

A: The details of the term given in Column A has been provided in following step and they are matched…

Q: Which of the following processes add diversity to antibody molecules AFTER encounte with antigen?…

A: Introduction Antibody diversity is a process by which antibodies are made diverse by switching to…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.