Determine the size of the DNA you would expect from the restriction digests of the GABRD and GABRD I284T PCRs. -Clearly write your null hypothesis for a chi-squared test of the viability of homozygous GABRD I284T variant. -Explain whether there is a difference in the levels of phosphorylated p44/42-MAPK antibodies and why you think that might be. Draw a diagram of a PCR cycle and give a hypothesis on how different GC content and different primer concentrations may effect the optimisation of a PCR. -Explain the process of agarose gel electrophoresis and how it is used to identify DNA fragments of different size, and what is the effect of using different agarose concentrations

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Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.