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Autosomal Recessive Inheritance We learned in the Linkage Mapping lab module the conventions for representing alleles in fruit flies. Recall that we use one to three letters, and the case (upper or lower) is determined by whether the mutant allele is recessive or dominant. Additionally, we add a "+" as a superscript to indicate the wild-type ("normal") allele. For example, if a new mutant phenotype is recessive, we can represent the recessive allele as m. Then the wild-type allele is mt, and m+ > m. Based on the rule of dominance, we can predict phenotypes based on genotypes: mm Wild type mm Wild type mm Mutant

Autosomal Recessive Inheritance We learned in the Linkage Mapping lab module the conventions for representing alleles in fruit flies. Recall that we use one to three letters, and the case (upper or lower) is determined by whether the mutant allele is recessive or dominant. Additionally, we add a "+" as a superscript to indicate the wild-type ("normal") allele. For example, if a new mutant phenotype is recessive, we can represent the recessive allele as m. Then the wild-type allele is mt, and m+ > m. Based on the rule of dominance, we can predict phenotypes based on genotypes: mm Wild type mm Wild type mm Mutant

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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This exercise primarily addresses o MLO 1: Correctly assign and interpret allele symbols according to the conventions of the fruit fly research community. o MLO 2: Correctly assign genotypes and phenotypes to parents and offspring in genetic crosses given a mode of inheritance. Autosomal Recessive Inheritance We learned in the Linkage Mapping lab module the conventions for representing alleles in fruit flies. Recall that we use one to three letters, and the case (upper or lower) is determined by whether the mutant allele is recessive or dominant. Additionally, we add a "+" as a superscript to indicate the wild-type ("normal") allele. For example, if a new mutant phenotype is recessive, we can represent the recessive allele as m. Then the wild-type allele is mt, and m+ > m. Based on the rule of dominance, we can predict phenotypes based on genotypes: mm Wild type Wild type Mutant m+m mm
Transcribed Image Text:This exercise primarily addresses o MLO 1: Correctly assign and interpret allele symbols according to the conventions of the fruit fly research community. o MLO 2: Correctly assign genotypes and phenotypes to parents and offspring in genetic crosses given a mode of inheritance. Autosomal Recessive Inheritance We learned in the Linkage Mapping lab module the conventions for representing alleles in fruit flies. Recall that we use one to three letters, and the case (upper or lower) is determined by whether the mutant allele is recessive or dominant. Additionally, we add a "+" as a superscript to indicate the wild-type ("normal") allele. For example, if a new mutant phenotype is recessive, we can represent the recessive allele as m. Then the wild-type allele is mt, and m+ > m. Based on the rule of dominance, we can predict phenotypes based on genotypes: mm Wild type Wild type Mutant m+m mm
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Step 1: Autosomal recessive Inheritance

Variations can be seen in both gene copies in each cell in autosomal recessive inheritance. An individual with autosomal recessive disorder has one copy of the mutated gene in each parent, but usually, neither parent exhibits the disease's symptoms. Typically, autosomal recessive illnesses do not impact every generation of a family.

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