Dent disease is reabsorption of filtered solutes and progressive renal failure. The following pedigree shows the pattern of inheritance for this disorder. On the basis of this pedigree, what is the most likely mode of inheritance for the disease? From your answer to part a, give the most likely genotypes for the following ersons in the pedigree: -1: 1-2: -5: Il-8: 1-1: IlIl-3:

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A:

Q: TO

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Q: None

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Inheritance and Mendelian Genetics

Inheritance means the passing of traits to offspring from parents. These traits could be passed either through asexual reproduction or sexual reproduction. The offspring receives the genetic material from the parents. Mendelian inheritance is a certain biological inheritance that follows the rules and principles laid down by Gregor Mendel in 1865. The initial hypothesis was considered wrong, but other inheritance theories modified the concept of inheritance and thus genetics.