Dent disease is reabsorption of filtered solutes and progressive renal failure. The following pedigree shows the pattern of inheritance for this disorder. On the basis of this pedigree, what is the most likely mode of inheritance for the disease? From your answer to part a, give the most likely genotypes for the following ersons in the pedigree: -1: 1-2: -5: Il-8: 1-1: IlIl-3:
Dent disease is reabsorption of filtered solutes and progressive renal failure. The following pedigree shows the pattern of inheritance for this disorder. On the basis of this pedigree, what is the most likely mode of inheritance for the disease? From your answer to part a, give the most likely genotypes for the following ersons in the pedigree: -1: 1-2: -5: Il-8: 1-1: IlIl-3:
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter4: Pedigree Analysis In Human Genetics
Section: Chapter Questions
Problem 8QP: Analysis of Autosomal Recessive and Dominant Traits In the following pedigree, assume that the...
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![MENDELIAN MODE OF INHERITANCE AND PEDIGREE ANALYSIS
1.
Dent disease is a rare disorder of the kidney in which there is impaired
reabsorption of filtered solutes and progressive renal failure. The following
pedigree shows the pattern of inheritance for this disorder.
a. On the basis of this pedigree, what is the most likely mode of inheritance for the
disease?
b. From your answer to part a, give the most likely genotypes for the following
persons in the pedigree:
1-1:
1-2:
Il-5:
Il-8:
III-1:
III-3:
IV-2:
IV-1:](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F1d6228d8-3f2f-4dea-b7bd-bd735c78d9c2%2F3222f696-8496-4136-84d4-44497f5eca9c%2F51qpu56q_processed.jpeg&w=3840&q=75)
Transcribed Image Text:MENDELIAN MODE OF INHERITANCE AND PEDIGREE ANALYSIS
1.
Dent disease is a rare disorder of the kidney in which there is impaired
reabsorption of filtered solutes and progressive renal failure. The following
pedigree shows the pattern of inheritance for this disorder.
a. On the basis of this pedigree, what is the most likely mode of inheritance for the
disease?
b. From your answer to part a, give the most likely genotypes for the following
persons in the pedigree:
1-1:
1-2:
Il-5:
Il-8:
III-1:
III-3:
IV-2:
IV-1:
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