According to a recent study, 1 out of 50,000 people will be diagnosed with cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene (dominant gene symbol is F and mutant is f). A. Using the rate of incidence above, what is the frequency of carriers of the cystic fibrosis allele for CFTR in the US? (3 pts) B. In a clinical study, 400 people from the population mentioned in (A.) were genotyped for BRCA1 Listed below are the results. Are these results in Hardy- Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts) BRCA1 genotype # of women 390 BB Bb bb 10 0 12pt Paragraph L BIUAV V T² v V

Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
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Chapter20: Chromosomes And Human Genetics
Section: Chapter Questions
Problem 6CT: About 4 percent of people of Northern European descent have a cystic fibrosis allele, but only about...
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According to a recent study, 1 out of 50,000 people will be diagnosed with
cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene
(dominant gene symbol is F and mutant is f).
A. Using the rate of incidence above, what is the frequency of carriers of the
cystic fibrosis allele for CFTR in the US? (3 pts)
B. In a clinical study, 400 people from the population mentioned in (A.) were
genotyped for BRCA1 Listed below are the results. Are these results in Hardy-
Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts)
BRCA1 genotype
# of women
390
BB
Bb
bb
10
0
12pt
Paragraph
L
BIUAV V
T² v
V
Transcribed Image Text:According to a recent study, 1 out of 50,000 people will be diagnosed with cystic fibrosis. Cystic fibrosis can be caused by a mutant form of the CFTR gene (dominant gene symbol is F and mutant is f). A. Using the rate of incidence above, what is the frequency of carriers of the cystic fibrosis allele for CFTR in the US? (3 pts) B. In a clinical study, 400 people from the population mentioned in (A.) were genotyped for BRCA1 Listed below are the results. Are these results in Hardy- Weinberg equilibrium? Use Chi Square to show whether or not they are. (3 pts) BRCA1 genotype # of women 390 BB Bb bb 10 0 12pt Paragraph L BIUAV V T² v V
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