5) AZT is a drug that is used to treat HIV/AIDS. When cells take up AZT, they convert it to AZT-triphosphate. AZT-triphosphate prevents the virus from synthesizing new DNA from its RNAcode.a. Write a 1-2 sentence explanation describing how AZT-triphosphate prevents DNAsynthesis. (4 points)HONH'N'O© ©N=N=NAZTb. Circle the location on AZT where the triphosphate group is appended (2 points) 5) AZT is a drug that is used to treat HIV/AIDS. When cells take up AZT, they convert it to AZT-triphosphate. AZT-triphosphate prevents the virus from synthesizing new DNA from its RNAcode.a. Write a 1-2 sentence explanation describing how AZT-triphosphate prevents DNAsynthesis. (4 points)HONH'N'O© ©N=N=NAZTb. Circle the location on AZT where the triphosphate group is appended (2 points)

Detailed Explanation: Question 3: Glutamine Structure at pH 7 At pH 7, the fully protonated form of…

Answered: 5) AZT is a drug that is used to treat…

Organic Chemistry

8th Edition

ISBN:9781305580350

Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote

Chapter28: Nucleic Acids

Section: Chapter Questions

Problem 28.7P

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264&OpenVellumHMAC-ab644d9786730f4650f72638a7bd0c5b#10001 Part A L Submit Part B amylose and cellulose Match the words in the left column to the appropriate blanks in the sentences on the right. a(16) B(14) a(12) glucose a(14) 8(16) a(12) fructose Request Answer a(12) B(16) a(16) cellulose and chitin Match the words in the left column to the appropriate blanks in the sentences on the right. glucose -tose also called - Search a(14) fructose 8(14) B(12) x | + Both are linear polysaccharides composed entirely of linkages are but in cellulose, they are Both are linear polysaccharides with 2 DELL and chitin contains N-acetylglucosamine. A Q Reset Help In amylose, the glycosidic glycosidic bonds. Cellulose contains he Reset Help ENG Constants
13 Which structure is NOT present in DNA? * (1 Point) A B D E NH2 NH2 H3C. N-H // N' NH2 H. H B D 14 Structure IV is an example of * (2 Points) OH H. но. -OH но- -H но- -H HO -H но - но- -H- но- H- но- -H но H Он H- -O- H- -OH- H- -OH H- -OH H- -OH OH H. Он но но HO. ÓH II IV V O aldonic acid O aldaric acid O ketopentose O aldohexose O pyranose 15 Atropine, ephedrine and reserpine are examples of * (2 Points) O glycosides O aminosugars fatty acids O alkaloids O uronic acids O O O O O O OO
Q23: Dr. Alghe has just performed a restriction digest on DNA she extracted from her samples. She must now run her DNA out on a gel to separate the fragments based on size. To do this she must prepare a 1.1% agarose gel, where the percentage is determined as mass/vol. How many grams of agarose must she add to 413 mL of buffer in order to arrive at the correct percentage? (answer to 2 decimals) **Assume the dissolution of agarose will not alter the final volume of the solution**
Section one. Match enzyme or molecule with its function in bacteria. Answers may be used more than once or not at all. DNA ligase d. tRNA promoter а. g. b. DNA helicase 1RNA h. terminator е. RNA polymerase f. DNA polymerase III i. stop codon с. 37. main enzyme in catalyzing DNA → mRNA transcription 38. unwinds double-stranded DNA at the replication fork 39. Where transcription stops 40. adds new DNA bases in the 5'→3’ direction 41. the "translator" molecule 42. contains codons 43. contains anti-codons
NH2 H2N-DNA- H N-DNA- H H2N-DNA- H2N. OCH3 H2N. HN-DNA- H3C NH H3C 'NH2 Mitomycin C DNA adduct Mitomycin C is an antitumor antibiotic that functions by forming cross-links in DNA chains. Draw curved arrows to show the movement of electrons in this step of the reaction mechanism. Arrow-pushing Instructions NH2 NH2 H H2N. но —СНз H2N. HO-CH3 N. NH H3C NH H3C TH. `H
DNA Replication1) Construct the complementary strand of DNA (strand II) that would pair with the DNA strand I sequence below. Remember that nucleotides are always added in the 5 prime to 3 prime direction. The base pairing rules are: DNA DNAadenine (A) always bonds with thymine (T) thymine (T) always bonds with adenine (A) guanine (G) always bonds with cytosine (C) cytosine (C) always bonds with guanine (G) STRAND I: 3’ T A C T A T A G T C T G T C T C C C A C T 5’ STRAND II: 5’ 3’
5:20 KB/s. 84% ← Seatwork 3-Nucleic acids.pdf Seatwork 3: Nucleotides and Nucleic acids A segment of DNA has the following sequence of bases ......5'-ATGCAATGATATTGAAGCTTA-3'...... a.) what sequence of bases would appear in mRNA transcribed from this segment b.) assume that the first base in this mRNA is the beginning of a codon. What order of amino acids would be translated into a polypeptide synthesized along this segment? c.) give anticodons for each tRNA associated with the translation in part (b) 」 о vo = III
Past paper question
1
I am not sure how to do number 10
Retroviruses like HIV, the pathogen responsible for AIDS, incorporate an RNA template that is copied into DNA duringinfection. The reverse transcriptase enzyme that copies RNA into DNA is relatively nonselective and error-prone, leadingto a high mutation rate. Its lack of selectivity is exploited by the anti-HIV drug AZT (3′@azido@2′,3′@dideoxythymidine),which becomes phosphorylated and is incorporated by reverse transcriptase into DNA, where it acts as a chain terminator.Mammalian DNA polymerases are more selective, having a low affinity for AZT, so its toxicity is relatively low.(a) Draw the structures of AZT and natural deoxythymidine.(b) Draw the structure of AZT 5′@triphosphate, the derivative that inhibits reverse transcriptase.*2
Which will have higher fluorescence intensity? A. 32 bp DNA segment B. 18 bp DNA segment

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