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- Explain how phenacetin result in toxicity in this reaction( explain the reaction)??? Toxicity by Sulfation • Sufation of N-hydroxylarylamines can generate reactive electrophile that can lead to hepatotoxicity and Carcinogenicity HO, & OEt phenacetin 7.127 ỎEt sulfotransferase 03SQ ÕEt :OEt 7.145 ÖEt OEt Protein nucleophile Attack here is also possibleNaOD, D20 What is the product?Complete the reaction given below.
- 29. The major product in the following reaction sequence is (i) mCPBA, NaHCO3 (ii) NaOH, H2O MeO (iii) I2, KI, NAHCO3, H20Provide the mechanism for the reacrion below.* Your answer is incorrect. Which synthetic route(s) would complete the reaction shown? Br ? 1 SO II O III O I and II Oland III OH + enantiomer HO Synthesis I: 1. NaCCCH3; 2. Na/NH3(1):3. OsO4; 4. NaHSO₂, H₂O Synthesis II: 2. NaCCCH3: 2. H₂, Lindlar's catalyst; 3. MCPBA: 4. aq. H₂SO4 Synthesis III: 1. NaCCCH3: 2. H₂, Pt: 3. MCPBA: 4. aq. H₂SO4
- 8. Draw the mechanism and product for the following reactions. (20 pts.) a. b. C. d. НОВИ H NaOCH2 половая CHO ZI CH3 1. Excess CHI, NaOH 2. Ag2O, Heat HO OH HOM HO CH3CH2NH2 H2SO4, H2O (pH 4.5) (CH3CH2)2NH H2SO4, H₂O (pH 4.5) mainedooM noilons A mains ooM mainedboMDraw the electrophile formed by the following reagents/conditions below.Provide a synthesis for the attached problem

