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- (A) Which is the anti-conformer of hexane in Newman projection? (B) Which is the equivalent structure of LAM in sawhorse representation? (C) Which is the most stable conformation of pentane in Newman projection?Consider the following two structures CI OH ОН ОН HOO H-CI HO- -H H- -ОН A) Determine the configuration of all stereogenic carbons in both structures (R vs. S). Show work! B) Convert the Fischer Projection to a bond-line structure. C) What is the relationship between the two structures? (identical, enantiomer, diastereomer, constitutional isomer, different/not an isomer)a) The Haworth projection of a-D-Mannose is given below. Draw theFischer projection (open form) and theHaworth projection for the B anomer (the other cyclic hemiacetal) of D-Mannose.
- Draw the planar (Haworth) structure for cis-1-ethyl-2- methylcyclohexane. (b) Draw the two ring - flipped chair conformations. (c) Circle the more stable chair conformation (circle both if they are equal in energy). Draw the Haworth structure and the two ring-flipped conformations of 1, 2, 4- trimethylcyclohexane (Compound D) on the frames below, b) Circle the more stable chair conformation (circle both if they are equal in energy). Haworth Structure(A) Indicate the positions (axial or equatorial) of the two substituents (a, b) in the most stable chair conformation. (B) Indicate the positions (axial or equatorial) of the two substituents (a, b) of Enantiomer in the most stable chair conformation. b4. Draw all possible stereoisomers of the following compounds. Assign the appropriate absolute (R/S) or geometric (E/Z) configuration to each of the stereoisomers (or double bonds) and label pairs enantiomers, diastereomers and meso compounds. (a) CH3CHBRCHOHCH3 (c) CH3CH=C(Br)CH=CHCI (e) CH3CH₂CHOHCHOHCH2CH3 (g) OH НО... CI (h) H3C Br (b) CH3CHBRCHBRCH ₂Br (d) CH3CH(C6H5)CHOHCH3 (f) CH₂(OH)CH2-CH(OH)CH=CHOH CH3 (1) Br HS Br
- 4. Do the following structures represent the same molecules or pairs of enantiomers? Additionally, convert the perspective structures to Fischer projections and vice versa. a. b. C. d. 11 CH HOH₂CH₂C-COH CH₂Br H₂C-CCI CH₂CH3 CH₂Br H-OH CH3 CI HỌC CHỊCH H CH₂CH3 CI HẠCH,C-C 'CH, CH₂Br H₂CH₂C-CH₂CH₂OH OH H HO-CH3 CH₂Br CH3 0-5-6-5 H+CI CH CH₂CH3Construct models of 1,2-dibromocyclopentaneand draw all the possible stereoisomers. Label each chirality centre with an*,andan Ror S. Indicate clearly which pairs are relatedasenantiomers and which as diastereoisomersor meso.(a) Draw all stereoisomers formed by monochlorination of the cis and trans isomers of 1,2-dimethylcyclobutane drawn below. (b) How many constitutional isomers are formed in each reaction? (c) Label any pairs of enantiomers formed.
- a). The Fischer projection of D-Galactose is given below. Draw Haworthprojections for the a and b anomers (both cyclic hemiacetals) of D-Galactose.Q8. Draw the two possible chair-like conformations of compound 1. Using the Çabo LAgld erelog priority rules, assign the absolute stereochemistry to each stereogenic centre contained in compound 1. NH2 'F 1Q7. Using the Cahn-Ingold-Prelog rule, assign the absolute stereochemistry to each stereogenic centre in compounds a-d, and determine whether they are chiral or not. a) b) OH OH H3C CH3 H3C CH3 NH2 c) d) OH H -0 H- H H3C* *CH3 OH OH ОН