5'--AUG UCG UAC ACU GCG --3' Make a change in this sequence. Write a different version of this sequence that has nonsynonymous (missense) mutation. Make a change in this sequence. Write a different version of this sequence that has a frameshift mutation.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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First
Second
Third
position
(5'end)
position
(3' end)
position
U
A
G
UAU TyrY
UAC Tyr
UAA Stop
UAG Stop
UUU Phe
- F
UUC Phe
UCU Ser
UCC Ser
UCA Ser
UCG Ser
UGU Cys
C
UGC Cys
UUA Leu
UUG Leu
UGA Stop
UGG Trp
W
CAU His L
CÁC His
CGU Arg
CGC Arg
CUU Leu
CCU Pro
CỤC Leu
FL
CUA Leu
ССС Pro
- P
CCA Pro
CAA GIn
Q
CAG Gln
R
CGA Arg
CGG Arg_
CUG Leu
CCG Pro
AUU lle
ACU Thr
AAU Asn
AGU Ser
ACC Thr
-T
ACA Thr
AUC le
AAC Asn.
AGC Ser
AAA Lys
K
AAG Lys
AGA Arg
-R
AGG Arg
AUA Ile
AUG Met
M
ACG Thr
GAU Asp
-D
GAC Asp_
GGU Gly
GGC Gly
GUU Val
GCU Ala
U
GCC Ala
- A
GCA Ala
GUC Val
G
GGA Gly
GGG Gly
- V
GAA Glu
-E
GAG Glu
GUA Val
A
GUG Val
GCG Ala
G
Nonpolar
Polar
Basic
Acidic
Stop codon
Table 4.1
Biology: How Life Works, Third Edition
© 2019 W. H. Freeman and Company
Consider this messenger RNA sequence:
5'-AUG UCG UAC ACU GCG --3'
• Make a change in this sequence. Write a different version of this sequence
that has nonsynonymous (missense) mutation.
• Make a change in this sequence. Write a different version of this sequence
that has a frameshift mutation.
UCAGI UCAG
UUAG
C.
A,
Transcribed Image Text:First Second Third position (5'end) position (3' end) position U A G UAU TyrY UAC Tyr UAA Stop UAG Stop UUU Phe - F UUC Phe UCU Ser UCC Ser UCA Ser UCG Ser UGU Cys C UGC Cys UUA Leu UUG Leu UGA Stop UGG Trp W CAU His L CÁC His CGU Arg CGC Arg CUU Leu CCU Pro CỤC Leu FL CUA Leu ССС Pro - P CCA Pro CAA GIn Q CAG Gln R CGA Arg CGG Arg_ CUG Leu CCG Pro AUU lle ACU Thr AAU Asn AGU Ser ACC Thr -T ACA Thr AUC le AAC Asn. AGC Ser AAA Lys K AAG Lys AGA Arg -R AGG Arg AUA Ile AUG Met M ACG Thr GAU Asp -D GAC Asp_ GGU Gly GGC Gly GUU Val GCU Ala U GCC Ala - A GCA Ala GUC Val G GGA Gly GGG Gly - V GAA Glu -E GAG Glu GUA Val A GUG Val GCG Ala G Nonpolar Polar Basic Acidic Stop codon Table 4.1 Biology: How Life Works, Third Edition © 2019 W. H. Freeman and Company Consider this messenger RNA sequence: 5'-AUG UCG UAC ACU GCG --3' • Make a change in this sequence. Write a different version of this sequence that has nonsynonymous (missense) mutation. • Make a change in this sequence. Write a different version of this sequence that has a frameshift mutation. UCAGI UCAG UUAG C. A,
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