4. A protein is found with the sequence Met-Thr-Tp-Phe-Lys-Cys-Arg-His-Pro-Gly, A mutant is found with the sequence Met-Thr-TIR-Phe-Lys. Assuming that the mutant resulted from a single base change in the DNA encoding the gene, what mutation took place at the DNA level and how did that affect the MRNA and protein sequence?
4. A protein is found with the sequence Met-Thr-Tp-Phe-Lys-Cys-Arg-His-Pro-Gly, A mutant is found with the sequence Met-Thr-TIR-Phe-Lys. Assuming that the mutant resulted from a single base change in the DNA encoding the gene, what mutation took place at the DNA level and how did that affect the MRNA and protein sequence?
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:eCt Would mutation M2 have on the protein produced?
4. A protein is found with the sequence Met-Thr-Im-Phe-Lys-Cys-Arg-His-Pro-Gly, A mutant is found with
the sequence Met-Thr-Trp-Rhe-Lys.
Assuming that the mutant resulted from a single base change in the DNA encoding the gene, what
mutation took place at the DNA level and how did that affect the MRNA and protein sequence?
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Step 1
Mutations are change in the nucleotide sequence which results in abnormalities in the protein product. Mutations are classified as Somatic mutation and Germline mutation based on the type of cell affected. Germline mutations are classified as Base substitution mutation, Sinlge base substitution, Insersion mutation, Deletion mutation, and Frame shift mutation. These are the mutations transferred genetically.
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