4. A protein is found with the sequence Met-Thr-Tp-Phe-Lys-Cys-Arg-His-Pro-Gly, A mutant is found with the sequence Met-Thr-TIR-Phe-Lys. Assuming that the mutant resulted from a single base change in the DNA encoding the gene, what mutation took place at the DNA level and how did that affect the MRNA and protein sequence?

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
icon
Related questions
Question
eCt Would mutation M2 have on the protein produced?
4. A protein is found with the sequence Met-Thr-Im-Phe-Lys-Cys-Arg-His-Pro-Gly, A mutant is found with
the sequence Met-Thr-Trp-Rhe-Lys.
Assuming that the mutant resulted from a single base change in the DNA encoding the gene, what
mutation took place at the DNA level and how did that affect the MRNA and protein sequence?
Investigate
Transcribed Image Text:eCt Would mutation M2 have on the protein produced? 4. A protein is found with the sequence Met-Thr-Im-Phe-Lys-Cys-Arg-His-Pro-Gly, A mutant is found with the sequence Met-Thr-Trp-Rhe-Lys. Assuming that the mutant resulted from a single base change in the DNA encoding the gene, what mutation took place at the DNA level and how did that affect the MRNA and protein sequence? Investigate
Expert Solution
Step 1

Mutations are change in the nucleotide sequence which results in abnormalities in the protein product. Mutations are classified as Somatic mutation and Germline mutation based on the type of cell affected. Germline mutations are classified as Base substitution mutation, Sinlge base substitution, Insersion mutation, Deletion mutation, and Frame shift mutation. These are the mutations transferred genetically.

steps

Step by step

Solved in 3 steps

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781319114671
Author:
Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:
W. H. Freeman
Lehninger Principles of Biochemistry
Lehninger Principles of Biochemistry
Biochemistry
ISBN:
9781464126116
Author:
David L. Nelson, Michael M. Cox
Publisher:
W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul…
Fundamentals of Biochemistry: Life at the Molecul…
Biochemistry
ISBN:
9781118918401
Author:
Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:
WILEY
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305961135
Author:
Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:
Cengage Learning
Biochemistry
Biochemistry
Biochemistry
ISBN:
9781305577206
Author:
Reginald H. Garrett, Charles M. Grisham
Publisher:
Cengage Learning
Fundamentals of General, Organic, and Biological …
Fundamentals of General, Organic, and Biological …
Biochemistry
ISBN:
9780134015187
Author:
John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:
PEARSON