The figure shows the position of two of these mutations a and b. The nucleotides are altered in these 2 different swo-1 mutant alleles. Use the genetic table to describe any AA changes. Name the type of mutation and describe its effect on swo-1 mRNA and protein for each of the mutations. 3. The swo-1 a mutation (insertion between C and G). 4. The swo-1 b mutation (C-to-T mutation for indicated C). 5. The swo-1 a mutation leads to worms with more body wall muscle, whereas worms with the swo-1 b mutation are not able to move. Based on these phenotypes and the findings from questions 3 and 4, describe the role the wild-type version of this protein plays in muscle function.

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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The figure shows the position of two of these mutations a and b. The nucleotides are altered in these 2 different swo-1 mutant alleles. Use the genetic table to describe any AA changes.
Name the type of mutation and describe its effect on swo-1 mRNA and protein for each of the mutations.

3. The swo-1 a mutation (insertion between C and G).

4. The swo-1 b mutation (C-to-T mutation for indicated C).

5. The swo-1 a mutation leads to worms with more body wall muscle, whereas worms with the swo-1 b mutation are not able to move. Based on these phenotypes and the findings from questions 3 and 4, describe the role the
wild-type version of this protein plays in muscle function.

swo-1 5'UTR
ATG: START
Swo-1a
ins-T
Swo-1b
C>T
-ACTGGTGACCACATGGGCGAAGCTTTCTCGCGAGGTAGTTAT.....continued
GCT
Transcribed Image Text:swo-1 5'UTR ATG: START Swo-1a ins-T Swo-1b C>T -ACTGGTGACCACATGGGCGAAGCTTTCTCGCGAGGTAGTTAT.....continued GCT
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