B-thalassemia is a hereditary blood disorder that leads to the formation of an abnormal hemoglobin which destroys red blood cells and causes anemia. Which of the following statements about patients with B-thalassemia is correct? 1. They express a longer version of the B-globin MRNA. 2. They have some intronic sequences in their B-globin mRNA. 3. They express a premature stop codon in their B-globin MRNA. 4. They express a longer version of the B-globin protein. A. 1, 2 and 3 O B. 1 and 3 O C. 2 and 4 D. 4 only O E. All of 1, 2, 3 and 4 are correct.

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Gene Interactions

When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.

Gene Expression

Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.