Sickle cell hemoglobin DNA CACGTAGACTGAGGACAC.. io.. A ... C... Sickle cell hemoglobin MRNA: Sickle cell hemoglobin Amino Acid sequence: 4. What type of mutation is this? Please explain why.

Q: Define mutation. Then describe the three basic types of mutation (substitutions, insertions, and…

A: A mutation is an alteration in the DNA sequence that mainly arises during the replication of DNA or…

Q: Using the DNA sequence above, write a new DNA sequence from 3’ to 5’ that incorporates a…

A: A missense mutation is a type of point mutation where a single nucleotide change in the DNA sequence…

Q: Why might some cells in the body, such as those in bonemarrow, be more susceptible to ribosomal…

A: Mutation It is the sudden heritable changes happening in the genotype of the organism which is…

Q: population in Africa is mozygous individuals carrying the Val-6 mutation die from sickle cel emia…

A: Sickle Cell anaemia is a genetic disease that results from a point mutation that results in the…

Q: Draw the SMN2 pre-mRNA (SMN2 has 10 exons and 9 introns), indicate the 5’ and 3’ SS location. [2pts]

A: Spinal muscular atrophy (SMA), which results from the deficiency of articulation of the endurance of…

Q: Can you please briefly define these five classes of domain folds.: α, β, α / β, α + β, and…

A: On a larger scale based on α and β secondary structures, the classes of domain folds are:- 1. α: In…

Q: (b) How many forms can naturally occurring DNA exist in? Explain how these forms are characterized.…

A: DNA  Deoxyribonucleic acid  Genetic material in many species Has ds(double stranded) structure…

Q: ckle-cell anemia is an interesting genetic disease. Normal homozygous individials (SS) have normal…

A:

Q: The initiation complex for translation includes transfer RNA-MET. Select an answer and submit. For…

A: During initiation,at the start of mRNA sequence the small ribosomal subunit binds.Then a tRNA…

Q: a. Identify the type of mutation shown below. b. How many amino acids are affected? c. What type of…

A: Ans a. The type of mutation shown below is point mutaion. A point mutation or replacement is a…

Q: 20. In class, we discussed different types of genetic change that can cause a normal gene (proto…

A: There are two common causes of most cancers involves mutations in genes called proto-oncogenes and…

Q: 45) A patient's mother died from an incurable neurological disease. The patient wants to test his…

A: Neurological diseases are a group of disorders that affect the nervous system, which includes the…

Q: In your earlier research for this case study, you have discovered that nucleotides 1591-1593 (in the…

A: Cystic fibrosis (CF) is a genetic disorder characterized by mutations in the cystic fibrosis…

Q: 19) Thalassaemia is a genetic disorder in which the red blood cells in the body cannot carry oxygen.…

A: Given: Thalassaemia is a genetic disorder in which the red blood cells in the body cannot carry…

Q: Most inherited forms of cancer involve _______________ and these individuals are for the mutation.…

A: Firstly we can examine what each of the terms given represents. 1. Tumor suppressor gene: It is a…

Q: 7) The protein VEGF plays an important role in stimulating the formation of new blood vessels. In…

A: VEGF ( vascular endothelial growth factor ) is responsible for the growth of new vessels. In…

Q: Which form of Retinoblastoma typically results in unilateral disease and exhibits 2-hit mutational…

A: Retinoblastoma is a cancer that affects the eyes. It is specifically a cancer of retinal layer of…

Q: [GAINI- is a protein coding gene that regulates cardiomyocyte metabolism in patients with heart…

A: Cardiovascular refers to the circulatory system. The circulatory system, which includes the heart…

Q: 32. A 23-year-old man comes to the physician because of a 1-month history of weakness and muscle…

A: Myoclonic epilepsy with ragged red fibers or MERRF syndrome is an inherited disease condition that…

Q: Mutations in the IL2RG gene cause approximately 30 percent of severe combined immunodeficiency…

A: Since we answer only three subparts of a question at a time, therefore we are answering the first…

Q: How do loss of function mutations associated with Artemis (protein) cause their resulting…

A: Introduction: -Artemis is a protein that in humans is encoded by the DCLRE1c gene.  Function: -…

Q: 1. A monogenic disease is a disease caused by a mutation in a single gene. For instance, sickle-cell…

A: * Sickle cell anemia is blood disorder in which red blood cells becomes mis shapen and turns into…

Q: What type of mutation is sickle cell anemia? Explain the molecular basis of sickle cell anemia.

A: Sickle cell anemia is an abnormal condition that arises due to the mutation in the beta-globin chain…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.