THEME I: Please label and rank the following point mutations in increasing order of their potential to change a protein product (assign number 1 to the most benign mutation, if two mutations have the same effect you can assign them the same rank)
THEME I: Please label and rank the following point mutations in increasing order of their potential to change a protein product (assign number 1 to the most benign mutation, if two mutations have the same effect you can assign them the same rank)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Step 1: Mutation and protein structure :
Label and rank of the given mutations in increasing (smaller to larger) order of their potential to change a protein structure :
A. Silent mutation; smallest change in protein structure.
C. Missence mutation; small change in protein structure.
E. Trinucleotide repeat (TNR) expansion; medium change in protein structure.
D. Frameshift mutation; larger change in protein structure.
B. Nonsense mutation; largest change in protein structure.
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