1) A drug was added to a cell with a resting membrane potential = -12mV. When added, the drug caused depolarization of membrane potential to -8 mV. Multiple answers:  Which of the following could have caused this change? Choose the best answers, all of which should be biological important/realistic mechanisms. a)Blockage of leak channels for potassium could have occurred b)Blockage of voltage-gated channels for potassium could have occurred c)Blockage of ligand-gated channels for potassium could have occurred d)Blockage of leak channels for sodium could have occurred e)Blockage of voltage-gated channels for sodium could have occurred f)Blockage of ligand-gated channels for sodium could have occurred g)Inhibition of the electrogenic function of the sodium-ATPase pump h)An action potential occurred I)The membrane had no potential energy to do work

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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1) A drug was added to a cell with a resting membrane potential = -12mV. When added, the drug caused depolarization of membrane potential to -8 mV.

Multiple answers:  Which of the following could have caused this change? Choose the best answers, all of which should be biological important/realistic mechanisms.

a)Blockage of leak channels for potassium could have occurred
b)Blockage of voltage-gated channels for potassium could have occurred
c)Blockage of ligand-gated channels for potassium could have occurred
d)Blockage of leak channels for sodium could have occurred
e)Blockage of voltage-gated channels for sodium could have occurred
f)Blockage of ligand-gated channels for sodium could have occurred
g)Inhibition of the electrogenic function of the sodium-ATPase pump
h)An action potential occurred
I)The membrane had no potential energy to do work
 
2) Multiple answers: Which area(s) of a bipolar neuron has a high density of leak channels for sodium and potassium? 

 answer choices

a)Dendrite membrane
b)Cell body/soma membrane
c)Initial segment/trigger zone
d)Axon
e)Axon terminal
 
3) At a resting membrane potential = -12mV, why does potassium have a net outward flux through a single leak channel?

answer choices

a)The efflux of potassium caused by the concentration gradient is lesser in effect than the influx along the electrical gradient

b)The influx of potassium caused by the concentration gradient is lesser in effect than the efflux along the electrical gradient

c)The efflux of potassium caused by the concentration gradient is greater in effect than the influx along the electrical gradient

d)The influx of potassium caused by the concentration gradient is greater in effect than the efflux along the electrical gradient

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