During extreme dehydration, plasma K* can increase to as high as 10 mM. (A) What would the membrane potential of this neuron be under these conditions? (Assume there are no other changes in ion concentrations.) (B) What would happen to the ability of the neuron in the preceding question to generate action potentials during extreme dehydration? Why might this be problematic? HINTS: You can assume that PK is 100 times the other Ps. Look up average AP threshold, in textbook or use value from next question to answer part B. Be careful how to handle [CI] because of its negative charge.

Human Anatomy & Physiology (11th Edition)
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Author:Elaine N. Marieb, Katja N. Hoehn
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During extreme dehydration, plasma K* can increase to as high as 10 mM. (A) What would the
membrane potential of this neuron be under these conditions? (Assume there are no other
changes in ion concentrations.) (B) What would happen to the ability of the neuron in the
preceding question to generate action potentials during extreme dehydration? Why might this be
problematic?
HINTS: You can assume that PK is 100 times the other Ps. Look up average AP threshold, in
textbook or use value from next question to answer part B.
Be careful how to handle [CI] because of its negative charge.
Transcribed Image Text:During extreme dehydration, plasma K* can increase to as high as 10 mM. (A) What would the membrane potential of this neuron be under these conditions? (Assume there are no other changes in ion concentrations.) (B) What would happen to the ability of the neuron in the preceding question to generate action potentials during extreme dehydration? Why might this be problematic? HINTS: You can assume that PK is 100 times the other Ps. Look up average AP threshold, in textbook or use value from next question to answer part B. Be careful how to handle [CI] because of its negative charge.
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