The endogenous ligand for an ion channel causes the influx of 50 Na+ ions per second. This ion channel has constitutive activity of 10 Na+ ions per second. If drug A binds to the ion channel and causes the influx of 50 Na+ ions per second, which of the following categories best describes drug A? Group of answer choices full agonist antagonist partial agonist inverse agonist
The endogenous ligand for an ion channel causes the influx of 50 Na+ ions per second. This ion channel has constitutive activity of 10 Na+ ions per second. If drug A binds to the ion channel and causes the influx of 50 Na+ ions per second, which of the following categories best describes drug A? Group of answer choices full agonist antagonist partial agonist inverse agonist
Phlebotomy Essentials
6th Edition
ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:Ruth McCall, Cathee M. Tankersley MT(ASCP)
Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
Section: Chapter Questions
Problem 1SRQ
Related questions
Question
The endogenous ligand for an ion channel causes the influx of 50 Na+ ions per second. This ion channel has constitutive activity of 10 Na+ ions per second. If drug A binds to the ion channel and causes the influx of 50 Na+ ions per second, which of the following categories best describes drug A?
Group of answer choices
full agonist
antagonist
partial agonist
inverse agonist
Expert Solution
Step 1
antagonist:A ligand that binds to a receptor and changes the receptor's state to cause a biological response is an antagonist.
Full agonist:A complete agonist activates the system's maximum reaction capacity.
partial agonist:Even with 100% receptor occupancy, a partial agonist falls short of the system's maximum response capacity.
When a full agonist is present, a partial agonist becomes an antagonist (if they compete for the same receptors)
inverse agonist:A ligand known as an inverse agonist decreases the proportion of receptors in an active state by binding to them.
Step by step
Solved in 2 steps
Recommended textbooks for you
Phlebotomy Essentials
Nursing
ISBN:
9781451194524
Author:
Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:
JONES+BARTLETT PUBLISHERS, INC.
Gould's Pathophysiology for the Health Profession…
Nursing
ISBN:
9780323414425
Author:
Robert J Hubert BS
Publisher:
Saunders
Fundamentals Of Nursing
Nursing
ISBN:
9781496362179
Author:
Taylor, Carol (carol R.), LYNN, Pamela (pamela Barbara), Bartlett, Jennifer L.
Publisher:
Wolters Kluwer,
Phlebotomy Essentials
Nursing
ISBN:
9781451194524
Author:
Ruth McCall, Cathee M. Tankersley MT(ASCP)
Publisher:
JONES+BARTLETT PUBLISHERS, INC.
Gould's Pathophysiology for the Health Profession…
Nursing
ISBN:
9780323414425
Author:
Robert J Hubert BS
Publisher:
Saunders
Fundamentals Of Nursing
Nursing
ISBN:
9781496362179
Author:
Taylor, Carol (carol R.), LYNN, Pamela (pamela Barbara), Bartlett, Jennifer L.
Publisher:
Wolters Kluwer,
Fundamentals of Nursing, 9e
Nursing
ISBN:
9780323327404
Author:
Patricia A. Potter RN MSN PhD FAAN, Anne Griffin Perry RN EdD FAAN, Patricia Stockert RN BSN MS PhD, Amy Hall RN BSN MS PhD CNE
Publisher:
Elsevier Science
Study Guide for Gould's Pathophysiology for the H…
Nursing
ISBN:
9780323414142
Author:
Hubert BS, Robert J; VanMeter PhD, Karin C.
Publisher:
Saunders
Issues and Ethics in the Helping Professions (Min…
Nursing
ISBN:
9781337406291
Author:
Gerald Corey, Marianne Schneider Corey, Cindy Corey
Publisher:
Cengage Learning