The endogenous ligand for an ion channel causes the influx of 50 Na+ ions per second. This ion channel has constitutive activity of 10 Na+ ions per second. If drug A binds to the ion channel and causes the influx of 50 Na+ ions per second, which of the following categories best describes drug A? Group of answer choices full agonist antagonist partial agonist inverse agonist

Phlebotomy Essentials
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ISBN:9781451194524
Author:Ruth McCall, Cathee M. Tankersley MT(ASCP)
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Chapter1: Phlebotomy: Past And Present And The Healthcare Setting
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The endogenous ligand for an ion channel causes the influx of 50 Na+ ions per second. This ion channel has constitutive activity of 10 Na+ ions per second. If drug A binds to the ion channel and causes the influx of 50 Na+ ions per second, which of the following categories best describes drug A?
Group of answer choices
full agonist
antagonist
partial agonist
inverse agonist
Expert Solution
Step 1

antagonist:A ligand that binds to a receptor and changes the receptor's state to cause a biological response is an antagonist.

Full agonist:A complete agonist activates the system's maximum reaction capacity.

partial agonist:Even with 100% receptor occupancy, a partial agonist falls short of the system's maximum response capacity.

When a full agonist is present, a partial agonist becomes an antagonist (if they compete for the same receptors)

inverse agonist:A ligand known as an inverse agonist decreases the proportion of receptors in an active state by binding to them.

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