Renko studied diffusion of tracer molecules to study paracellular diffusion across an epithelial monolayer of Caco-2 cells. The tracers were fluorescently labelled dextran molecules of different molecular weight. She is screening various drugs to determine whether they affect the cells in any way. Which drugs are most likely to change paracellular diffusion? a.) Drugs that modify microvilli are the most likely to change paracellular diffusion b.) Drugs that modify gap junctions are the most likely to change paracellular diffusion c.) Drugs that modify with
Dr Renko studied diffusion of tracer molecules to study paracellular diffusion across an epithelial monolayer of Caco-2 cells. The tracers were fluorescently labelled dextran molecules of different molecular weight. She is screening various drugs to determine whether they affect the cells in any way. Which drugs are most likely to change paracellular diffusion?
a.) Drugs that modify microvilli are the most likely to change paracellular diffusion
b.) Drugs that modify gap junctions are the most likely to change paracellular diffusion
c.) Drugs that modify with aquaporins are the most likely to change paracellular diffusion
d.) Drugs that modify tight junctions are the most likely to change paracellular diffusion
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