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Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question

In the recording below, a neuron was bathed in a saline solution containing a pharmacological
agent that altered the membrane currents being recorded.

a) What ionic current is being recorded in these data?

b) What pharmacological agent was likely used in this study and what did it do?

c) Is the recorded ionic current transient or sustained and why?
d) What is the role of this ionic current in the production of a neuronal action potential?

Membrane Potential
100
S0
1-50
300
200
100
-100
-200
-300
Mambrane Potential (mV)
Current (nA)

Expert Solution

Step 1

An action potential is triggered by a graded potential that causes the membrane to depolarize until it reaches the threshold for activation of voltage-gated Na⁺ channels.
The inward flow of sodium ions increases the concentration of positively charged cations in the cell and causes depolarization

Action potential occurs when a neuron sends information down an axon, away from the cell body.
Na⁺ is critical for the action potential in nerve cells

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